Testosterone Gels

Recommended by Dr. Michael White, Updated on December 27th, 2017
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Testosterone cypionate is a type of anabolic steroids used to increase muscle mass while decreasing fat mass. As testosterone cypionate is considered to have a perfect score with regard to its anabolic rating, it is used as a bench mark and comparison with most other anabolic steroids. Cypionate is taken usually via injection, but also could be administered using an oral pill, or with an adhesive skin patch.

Testosterone Cypionate Injection, for intramuscular injection, contains Testosterone Cypionate which is the oil-soluble 17 (beta)- cyclopentylpropionate ester of the androgenic hormone testosterone.

The chemical name for Testosterone Cypionate is androst-4-en-3-one,17-(3-cyclopentyl-1- oxopropoxy)-, (17)-. Its molecular formula is C27H40O3, and the molecular weight 412.61.

About 90 percent of a dose of testosterone is excreted in the urine as glucuronic and sulfuric acid conjugates of testosterone and its metabolites; about 6 percent of a dose is excreted in the feces, mostly in the unconjugated form. Inactivation of testosterone occurs primarily in the liver. Testosterone is metabolized to various 17-keto steroids through two different pathways. The half-life of Testosterone Cypionate when injected intramuscularly is approximately eight days.

Inmost tissues the activity of testosterone appears to depend on reduction to dihydrotestosterone, which binds to cytosol receptor proteins. The steroid-receptor complex is transported to the nucleus where it initiates transcription events and cellular changes related to androgen action.

Tesosterone Cypionatecauses retention of nitrogen, sodium, potassium, and phosphorous, and decreased urinary excretion of calcium. Androgens have been reported to increase protein anabolism and decrease protein catabolism. Nitrogen balance is improved only when there is sufficient intake of calories and protein.

Prolonged use of high doses of androgens (principally the 17- alkyl-androgens) has been associated with development of hepatic adenomas, hepatocellular carcinoma, and peliosis hepatis all potentially life-threatening complications.

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Testosterone Gels

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