Male Hypogonadism is a relatively common medical condition that afflicts men of all ages but is most common among men forty and over. Symptomatic Testosterone Deficiency is believed to afflict 5% of men in America but becomes increasingly likely as men grow older. It's estimated that around 6.5 million men across the United States struggle with Low-T. By age 70, almost 20% of men have significant symptoms directly attributable to declining Testosterone Levels.
Video Download: Risk Factors For And Causes Of Male Hypogonadism
Video Stream: Risk Factors For And Causes Of Male Hypogonadism
Types of Hypogonadism: Primary and Secondary Hypogonadism
Primary Hypogonadism is any form of Testosterone Deficiency that results in a direct inability of the testes to adequately produce Testosterone. Primary Hypogonadism is often the result of genetic conditions such as Klinefelter's syndrome, which is the result of boys conceived with two X chromosomes.
In adults, Primary Hypogonadism is generally the result of conditions which directly impact or damage the testes, such as cancer, radiation treatments, surgery, and physical trauma. There are also many medications which can suppress testicular activity, such as neoplastic agents (including busulfan, cyclophosphamide, cisplatin, and chlorambucil), ketoconazole, and glucocorticoids.
Secondary Hypogonadism is the most common form of Testosterone Deficiency. Rather than being a deficiency directly related to impaired testicular function, Secondary Hypogonadism is the result of impaired upstream signaling, resulting primarily from diminished or non-production of Gonadotropin-Releasing Hormone (GnRH). In many cases, Low Testosterone Levels are paired with low levels of Follicle-Stimulating Hormone and Luteinizing Hormone in the case of Secondary Hypogonadism.
While Secondary Hypogonadism can be the result of congenital issues, this is quite rare. In children and adults, many medications can impair Testosterone Production via the suppression of Testosterone Secretagogues, including opiates, glucocorticoids, and steroids. The most-experienced form of Secondary Hypogonadism is Andropause, also known as Age-Related Testosterone Deficiency. As men grow older, their ability to produce Testosterone naturally diminishes slowly over time, a direct result of reduced upstream signaling to the testes and adrenal glands for Testosterone Production.
Symptoms of Hypogonadism in Men
Because Testosterone is the primary source of physiological masculinity, Testosterone Deficiency has widespread effects on form and function. The most well-known aspects of Hypogonadism are low libido and sexual dysfunction, but Low-T causes far more significant and broader issues. Testosterone promotes healthy body composition, and when Testosterone Levels fall too far, it leads to both increased body fat and reduced muscle mass. Psychologically, hypogonadism is strongly associated with depression, anxiety, and trouble sleeping. Testosterone also has a substantial protective effect on the heart, and Hypogonadism has a dangerous correlation with a heart attack and heart disease. Significant Hypogonadism can lead to fertility issues, anemia, auxiliary hair loss, and more.
The symptoms of Hypogonadism are also strongly associated with age-of-onset. Children suffering from Hypogonadism experience delayed the onset of puberty, femininization, and other significant symptoms resulting from the developmental influence of Testosterone during adolescence. These symptoms can be relieved via Testosterone Replacement Therapy. Prenatal Testosterone Deficiency is generally the result of genetic defects and can have extreme developmental consequences.
Obesity, Bodyfat, and Hypogonadism
A primary risk factor for Testosterone Deficiency and Low-T is Obesity. Adipose fat cells, which congregate around the hips and midsection, have a nasty side-effect of converting Testosterone into Estrogen. In a healthy body composition, there is a balance which strongly favors normal Testosterone Levels. The more that you weigh, however, the stronger of an influence that body fat has upon your Serum Testosterone. If you are overweight or obese, one of the best things that you can do to improve your Testosterone Balance is to lose weight.
Diabetes and Hypogonadism
Diabetes is a chronic medical condition which has a significant impact on Testosterone Levels. Just being overweight or obese increases the risk of Low-T, but the threats compound with Diabetes. Studies have shown that around 1/3rd of patients that are simultaneously obese and suffering from Type-2 Diabetes struggle with significant Testosterone Deficiency. If you are experiencing Diabetes and are overweight, losing weight can help increase Testosterone Levels, but it still appears that Type-2 Diabetes has a negative influence on Testosterone Levels at any bodyweight. Recent studies have shown that Bio-Identical Testosterone may have a positive impact on wellness and health among Type-2 Diabetes Patients.
Alcohol and Hypogonadism
Drinking has a negative impact on Testosterone Production and contributes to Hypogonadism. Drinking too much alcohol suppresses the function of the testes, which leads not only to suppressed Testosterone Production but also diminished fertility and sperm count. Alcoholism can even directly damage testicular tissue. It's a common issue among heavy drinkers to have an impaired libido. If you are a moderate to heavy drinker and have been having problems with erectile dysfunction and low libido, cutting back on alcohol may have a miraculous effect on your sexual function.
Sedentary Lifestyle and Testosterone Deficiency
Testosterone is produced mainly as a consequence of physical activity. Your body responds to physical exertion of the muscles by elevating Testosterone Production. Exercises which work out large groups of muscles have been shown to provide a burst of Testosterone. On the other hand, this means that an inactive lifestyle has a tremendously negative impact on Testosterone Levels. Sadly, this phenomenon feeds upon itself.
If you aren't up and moving, your body isn't making Testosterone. If your body doesn't produce enough Testosterone, then you'll have significant issues with fatigue and diminished exercise capacity. The best way to combat this cause of Hypogonadism is to force yourself to get up and to move by any means necessary. Start slow, and you'll find yourself energized and happier in no time!
Stress and Testosterone Deficiency
One of the primary factors of hormone imbalance is stress. The human body ultimately has a maximum reserve of hormones that it can produce. Many of these hormones are highly beneficial to preserving your long-term health, including Testosterone and Human Growth Hormone. Others deliver benefits in the short term, like Endorphins and Cortisol. Cortisol is the body's primary response to stress. It prepares the human body for fight-or-flight. It sets you up for snap decisions and decisive action. The problem with Cortisol is when you produce too much of it too frequently.
Physical and psychological stress are intrinsically linked, and too much of either for too long will have a negative impact on your long-term hormone balance. If you live a lifestyle that's high in stress, or you have issues with stress management, then taking steps to improve your stress levels will have a positive impact on your hormone balance.
- Testosterone Replacement Beneficial for Modern Men? - February 11th, 2020
- NATESTO (testosterone) Nasal Spray - October 30th, 2019
- Ordering Testosterone Replacement Therapy (TRT ) Buy It Online - July 19th, 2019
- Low T - My life was falling apart because I had low testosterone - April 16th, 2019
- Testosterone cream and gel for supplementation treating hypogonadism - April 9th, 2019
- Testosterone Treatments May Alleviate Negative Effects of Type-Two Diabetes - March 20th, 2019
- Clomiphene Citrate for Low-T - August 20th, 2018
- Excessive Use of Tylenol / Acetaminophen May Negatively Affect Testosterone Levels in Unborn Boys - August 9th, 2018
- What Is Male Hypogonadism - July 25th, 2018
- More than 152 Million Men Suffer from Hypogonadism and Low Testosterone - July 17th, 2018
- HIV and Testosterone Deficiency - verywell.com - July 17th, 2016
- Hypogonadism - UT Medical Center - July 17th, 2016
- Hypogonadism - Definition, Causes, Symptoms and Treatment - July 17th, 2016
- Lipocine - Hypogonadism - July 17th, 2016
- Hypogonadism - Risks, Symptoms and Leading Causes | Treato - July 17th, 2016
- Hypogonadism and Hypogonadism Resources - What is ... - July 17th, 2016
- Male Hypogonadism - Genitourinary Disorders - Merck ... - July 9th, 2016
- Hypogonadism - May 6th, 2016
- Male - Hypogonadism -- Low T Treatment Help!? - Drugs.com - May 6th, 2016
- Hypogonadism Causes Infertility. Learn how to detect and ... - May 6th, 2016
- BodyLogicMD - Hypogonadism (Low Testosterone in Men) - February 8th, 2016
- Hypogonadism | Disorders | Knowledge Base - August 26th, 2015
- hypogonadism | pathology | Britannica.com - July 22nd, 2015
- Male hypogonadism Tests and diagnosis - Mayo Clinic - May 23rd, 2015
- Hypogonadism (Medical Condition) - Video - April 21st, 2015
- Treatment Options for Hypogonadism - Healthline - April 4th, 2015
- Hypergonadotropic hypogonadism - Wikipedia, the free ... - March 23rd, 2015
- Testosterone treatment of male hypogonadism - UpToDate - March 23rd, 2015
- Statins may lower testosterone and libido - March 16th, 2015
- Hypogonadotropic Hypogonadism - Pipeline Review, H1 2015 - March 13th, 2015
- Biomarker monitors testosterone therapy for osteoporosis - March 12th, 2015
- The effect of hypogonadism and testosterone-enhancing therapy - Video - March 5th, 2015
- Causes of secondary hypogonadism in males - March 2nd, 2015
- Male hypogonadism: symptoms, cause, treatment, risk ... - February 18th, 2015
- Male Hypogonadism 1/28/15 - Video - January 31st, 2015
- What is Hypogonadism - Symptoms and Treatment | Hormone ... - January 30th, 2015
- Auxilium Announces Results from Special Meeting of Stockholders - January 28th, 2015
- Male hypogonadism pathophysiology - Video - January 14th, 2015
- Endo to Acquire Rights to Testosterone Nasal Gel Natesto - Analyst Blog - November 26th, 2014
- Female Hypogonadism Symptoms | eHow - November 23rd, 2014
- Testosterone Deficiency (Hypogonadism) Overview ... - November 23rd, 2014
- Male Hypogonadism Therapeutic Pipeline Industry Review, H2 2014 - Video - November 7th, 2014
- Hypogonadism in men living with HIV - Video - November 7th, 2014
- Will Repros (RPRX) Miss Estimates This Earnings Season? - Analyst Blog - November 5th, 2014
- Urology Care Foundation - Urology A-Z - Low Testosterone - November 3rd, 2014
- Male Hypogonadism: Male Reproductive Endocrinology: Merck ... - October 28th, 2014
- Hypogonadism Wikipedia - October 28th, 2014
- Hypogonadism No Moustache! No Beard!! - October 28th, 2014
- Apricus expands development pipeline with the in-licensing of US rights for fispemifene, a phase 2b ready asset, from ... - October 21st, 2014
- Apricus expands development pipeline with in-licensing of US rights for fispemifene - October 21st, 2014
- The Wall Street Journal: Repros Therapeutics shares drop on drug application setback - October 18th, 2014
- Repros Therapeutics Analyst Brief Report; Androxal(R) Achieves Superiority in Top Line Analysis by Small Cap Street ... - September 30th, 2014
- Repros Reports Encouraging Late-Stage Data on Androxal - Analyst Blog - August 28th, 2014
- Repros Therapeutics Q2 Loss a Penny Wider than Expected - Analyst Blog - August 12th, 2014
- Prevalence, Diagnosis and Treatment of Hypogonadism in ... - April 30th, 2014
- Repros Completes Enrollment for Androxal Study - Analyst Blog - April 16th, 2014
- VLog #127 Frances Explains Hypogonadism. - Video - April 7th, 2014
- Hypogonadism: Types, Causes, & Symptoms - Medical ... - April 6th, 2014
- Male hypogonadism Symptoms - Diseases and Conditions ... - April 2nd, 2014
- Update on Endo's Product Portfolio - Analyst Blog - March 11th, 2014
- Unit Project 1 Hypogonadotropic hypogonadism - Video - March 8th, 2014
- Endo: FDA Oks AVEED Injection For Treatment Of Adult Men With Hypogonadism - March 6th, 2014
- Hypogonadism | Medscape - Latest Medical News, Clinical ... - February 23rd, 2014
- Hypogonadism : Types, Causes, & Symptoms - Healthline - February 17th, 2014
- Low Testosterone (Hypogonadism) in Men - Video - February 14th, 2014
- Hypogonadism: Types, Causes, & Symptoms Healthline - February 14th, 2014
- Testosterone Therapy Not Always Good for Older Men - February 11th, 2014
- Repros Shares Soar After FDA Meeting - Analyst Blog - February 8th, 2014
- Endocrine Society calls for large-scale studies to evaluate testosterone therapy risks - February 8th, 2014
- Study Finds Potential Heart Risks from Testosterone Therapy - February 3rd, 2014
- Hypogonadism - SharedJourney - January 23rd, 2014
- Repros Continues to Gain on Androxal News - Analyst Blog - January 15th, 2014
- Hypogonadism | Medscape - Latest Medical News, Clinical Trials ... - December 30th, 2013
- Hypogonadism - HealthCentral - December 24th, 2013
- Hypogonadism - December 23rd, 2013
- Hypogonadism - Medscape Reference - December 21st, 2013
- Audio-Digest Foundation Announces the Release of Oncology Volume 04, Issue 16: Highlights from Future Directions ... - December 15th, 2013
- Male hypogonadism: Symptoms - MayoClinic.com - December 12th, 2013
- Exciting medical advances using HRT - December 12th, 2013
- Hypogonadism - About.com Men's Health - December 2nd, 2013
Contact Us Now
Word Count: 1085