American Testosterone Clinic for Men

Reading Time: 2 minutesIntroduction to Androgen Action Androgens, primarily testosterone and its more potent derivative dihydrotestosterone (DHT), play pivotal roles in the development and maintenance of male characteristics. These hormones exert their effects by binding to the androgen receptor (AR), a member of the nuclear receptor superfamily. This interaction initiates a cascade of molecular events that ultimately influence gene expression and cellular function. Understanding the intricacies of androgen action is crucial for developing targeted therapies that can modulate these pathways for therapeutic benefit in American men. Molecular Mechanisms of Androgen Signaling Upon binding to androgens, the AR undergoes a conformational change, dissociating from … Read more »

Reading Time: 2 minutesIntroduction Transgender men, individuals assigned female at birth who identify as male, often seek hormone therapy to align their physical appearance with their gender identity. This article delves into the endocrine evaluation and management of hormone therapy for transgender men, focusing on evidence-based protocols that are crucial for achieving optimal health outcomes. Endocrine Evaluation Prior to Hormone Therapy Before initiating hormone therapy, a comprehensive endocrine evaluation is essential. This evaluation should include a detailed medical history, physical examination, and baseline laboratory tests. Key assessments include measuring serum levels of testosterone, estradiol, and other relevant hormones to establish a starting point … Read more »