Treatment Options for Hypogonadism – Healthline

Recommended by Dr. Michael White, Updated on November 6th, 2020

Hypogonadism is a condition that results in lowered function of the testis in males or ovaries in females. This condition can be present at birth, but may also develop after infection or injury.

There are two types of hypogonadism. Primary hypogonadism is caused by a problem with the testis or the ovaries. Secondary hypogonadism (hypogonadotropic hypogonadism) is caused by pituitary or hypothalamic gland disorders.

Complications of hypogonadism in newborns may include abnormal genitals. In pubescent boys, lack of treatment can result in impaired genital growth, absence of body hair, and enlarged breasts. Complications in untreated adult males include:

Complications in females include:

The main treatment is hormone replacement therapy, but your course of treatment will be determined by the exact cause. In most cases, treatment results in substantial improvement.

If your condition is caused by testicular failure, testosterone replacement therapy (TRT) can:

In boys, low doses of testosterone over time can be used to replace naturally occurring testosterone during puberty. This also decreases the probability of negative side effects. For boys, TRT can stimulate puberty and:

Women who have a decreased sex drive may benefit from low-dose testosterone. TRT can be administered is several ways, such as:

Discuss the pros and cons of each of these methods with your doctor.

Pre-menopausal women can benefit from estrogen that comes in pill or patch form. Estrogen and progesterone are sometimes combined to lower the chances of a woman developing endometrial cancer.


Treatment Options for Hypogonadism - Healthline

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