Health Column: Anti-aging strategies

Recommended by Dr. Michael White, Updated on November 4th, 2020
Reading Time: 2 minutes

The goal of anti-aging is to slow, stop, or even reverse many of the changes associated with aging. This means staying healthy, active, and vibrant of body and mind, while avoiding the common diseases and infirmities of aging. A cornerstone of anti-aging strategy is to replace the hormones that naturally decline with aging, including the sex hormones estrogen, progesterone, and testosterone, as well as a few adrenal hormones.


The science of aging reveals we are designed to reproduce and to survive. Once accomplished, by about middle age our genetic replication starts increasing in mistakes, enzymes slow in catalyzing chemical reactions, and hormones decline. Aging begins

HRT is really about preventing disease and maintaining quality of life. Its about keeping the body operating well. Not having optimal hormone levels is like letting a fine automobile just run out of oil, then declaring it is growing old as the red light comes on and it overheats.

After menopause female sex hormone production dramatically plummets, and while the same thing happens to men at andropause, it occurs at a slower rate. One result of hormone decline is physical aging meaning thin bones, loss of muscle mass, fat accumulation and loss of skin elasticity and radiance. For women, vaginal dryness, and for men, erectile dysfunction, are directly related to low-hormone levels.

Mental aging related to low sex hormones includes many symptoms, such as depressed mood, anxiety, insomnia, fatigue, brain fog, lack of motivation, and low sex drive. Increased rates of diseases are associated with low sex hormones, including heart disease, osteoporosis, diabetes, dementia and certain cancers.

The adrenal hormones decline about the same in men and women, and similar to testosterone in men, they drop slowly over time. By age 50 many people are already low on two key adrenal hormones, pregnenolone and DHEA (de-hydro-epi-androsterone).

Pregnenolone is known for its role in mental processing and memory. It is also produced in the brain and has been shown to play a role in the creation of memory as well as protecting the nerve circuits that preserve memory. Scientists believe that the hormone pregnenolone has vast potential for maintaining healthy cognitive function and may be the most potent memory enhancer yet reported.

Research shows that low pregnenolone correlates with Alzheimers dementia. Pregnenolone stimulates the growth of new nerves in the brain and increases a memory enhancing neurotransmitter called acetylcholine. Further studies show that supplementing pregnenolone can reverse memory deficits. It also has the amazing ability to stimulate nerve transmission while some of its metabolites actually calm over-excited nerve tissue. This makes pregnenolone sharpen memory and cognition while helping conditions such as anxiety.

DHEA is made from pregnenolone and has a wealth of benefits including musculoskeletal support, promotion of mental health, immune system regulation and maintaining cardiovascular health. Good for bones, muscle and metabolism, DHEA has been shown to increase bone mineral density, increase muscle mass and stimulate breakdown of fat leading to weight loss.

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Health Column: Anti-aging strategies

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