Category Archives: Testosterone Information

Testosterone: How long does it take to see benefits? Frequently some of the most common questions our endocrinologists get asked by our new patients about testosterone cream, gel or shots are: 1. How long does testosterone therapy take to work? 2. When will I start feeling better? 3. How soon can I expect to see results? 4. How much time does testosterone take to see the benefits? The short answer is most patients notice changes in how they feel on the inside within one or two weeks, but that doesn't always apply to everyone because of the physical differences in people. The physiology of each patient is varied. Some patients start feeling better from day 1 or 2 of starting TRT. Others patients can take a much longer time, and that means it can take them about one or two months depending, but this long period tends to be rare. The majority of people experience changes within days or weeks of starting TRT testosterone replacement therapy. The best way to determine how long it is going to take before you start noticing differences are based on many factors. What we have seen that has the most significant impact is exercise, even more so than diet changes. Sleep, Sex … Read more »

Time magazine ran a cover story on "manopause" this week, based on a recent University of Sydney study that found the testosterone industry globally is booming, especially among middle-aged and older men who want to increase longevity and libido, boost energy and “power, passion and performance." And There's Good Reason Why  Testosterone is what makes men MEN. Strength, energy, a healthy immune system, pain-free joints, the ability to recuperate from a grueling workout and come back the next day for more, staying sharp mentally, enjoying a great sex life and possessing the capacity to still perform...all of these are directly related to a man's testosterone level. When we consider all of the benefits that testosterone delivers, it is easy to see why the industry is experiencing such exploding growth. In fact, the question is not why that's happening. The real problem is why every man in the world is not doing something to replenish his testosterone levels, levels that begin to drop off around the age of 30 at a rate of approximately 10% per decade. Across the U.S., as well as the entire world, men are jabbing themselves with needles, wiping on gels, sticking on patches, and inserting implants … Read more »

Testosterone. It's the magic hormone that turns boys into men. It is an essential hormone that all men need to produce to be masculine. High levels of testosterone are associated with masculine features such as body hair, a hoarse voice, and muscles. But that's far from all that it does. Testosterone delivers some significant health benefits as well. If you want to know why testosterone is healthy for you, consider this: young men are flooded with testosterone. Regrettably, men begin to lose their testosterone supply when they reach the age of 30, and this continues at approximately 10% per decade. Is it merely coincidence that older men have far more health problems than younger ones? Very doubtful. Here are some of the best-known health benefits that men derive from this all-powerful hormone: Boosts red blood cell count. A boost of testosterone helps increase your red blood cell count (RBC). That is one of the reasons why men have higher levels of RBC and hemoglobin than women. If you are losing a ton of blood, it can be a lifesaver. Adds muscle mass. Check out competitive bodybuilders, or any muscular man. Do you think they are suffering from low levels of … Read more »

Lipocine Inc. (LPCN) may have a massive hit on its hands with the first swallowable oral testosterone treatment. Oral testosterone could revolutionize the testosterone market because users usually have to inject themselves or use a gel that absorbs through their skin. The problem with these two delivery methods is that they are inconvenient and may transfer to women and children. These issues may deter potential users. The investment firm Canaccord Genuity sees a significant upside here. The company's Corey Davis and Lidia Liu initiated coverage of Lipocine with a Buy rating and assigned it a $15.00 price target. If the firm is correct in its assessment, then Lipocine shares could rise more than 80% if the outcome expectations live up the scenario outlined in this analyst call. The way the firm arrived at the target price of $15.00 was a discounted price-to-earnings (P/E) valuation, applying a multiple of 20 to the 2021 earnings per share target $2.06, and then cut by 20% for five and a half years. The potential risks to this analysis include failure to gain FDA approval, to find a partner or to sell the company. Canaccord Genuity's analyst Corey Davis said: “Lipocine is on the verge … Read more »

Recently, the only methods to deliver testosterone replacement therapy (TRT) were to receive an injection, swallow pills or apply a topical gel. However, a new approach has emerged that is more convenient for some. TRT is now available using a nasal gel that raises men’s low testosterone levels to normal, with few side effects. This exciting development is based on the results of the phase 3 clinical trial to be presented at the Endocrine Society’s 97th annual meeting in San Diego. Last May, the U.S. Food and Drug Administration (FDA) approved the drug called Natesto, which is the only FDA-approved nasal testosterone replacement therapy, according to the manufacturer, Trimel Pharmaceuticals. Under the terms of the agreement, Trimel will receive an upfront payment of $25 million and could receive additional payments upon the achievement of certain regulatory and sales milestones. Under the terms of the agreement, Trimel will be solely responsible for the manufacture and supply of Natesto, and Endo receives exclusive commercial rights to the Natesto product in the US and Mexico. Also, Endo will collaborate on all regulatory and clinical development activities in coordination with Trimel. And, Endo will pay a tiered supply price for the product. Endo expected … Read more »

Prescriptions for testosterone have become big business in America, but doctors and researchers disagree on whether it’s safe or not. A Testosterone Boost May Restore Many of Your Youthful Traits but Know the Possible Health Risks One elderly gentleman described the feeling when his sex drive began to diminish as he aged. “It was like becoming unchained from a maniac,” in what has been described as a mixture of relief and nostalgia. He didn't discuss testosterone replacement therapy, but an ever-increasing number of over-50 men are determined to reconnect with their personal maniac. Testosterone Replacement Therapy = Big Business Across America, a chain of 49 (and growing) clinics referred to as “Low T Centers,” have sprung up to handle the demand, promising “power, performance, and passion.” The number of prescriptions for testosterone in America has skyrocketed ten times between 2000 and 2011. Low T currently serves 45,000 patients at an average price of $400 a month — no question about it. Testosterone replacement therapy is big business. Low T is just the latest solution for the missing maniac that stretches back in time...way, way back. It was Socrates who first noticed him. Other attempts to regain that thriving, youthful libido … Read more »

The sweet-smelling soap you're using to wash your hands and body could be wiping out your testosterone. In fact, multiple studies are linking low testosterone to two insidious chemicals: Triclosan and Triclocarban. These compounds are found seemingly everywhere, from bar soap to toothpaste, and even in some kitchen supplies like cutting boards and sponges. The Food and Drug Administration (FDA) is in the middle of what's called a monograph, which means they're investigating the safety of the chemicals. And the companies who make antibacterial soaps will have to prove that the benefits of their products outweigh the health risks. "Both chemicals affect testosterone production in men, as well as thyroid functions and endocrine systems as well," explains Dr. Todd Howell, the Medical Director for The Aesthetic Medicine and Anti-Aging Clinics of Louisiana. The FDA approved the use of Triclosan and Triclocarban in 1993. Companies use the products to make their products antibacterial or antimicrobial. Howell explains that "I wouldn't go as far as saying all antibacterial soaps are bad. You want to pick up your product and look at the label and look for triclosan or triclocarban." Over the past 20 years, testosterone levels in adult men in the U.S. … Read more »

Testosterone Replacement Therapy DOES NOT Increase Heart Attack Risk Recently, the mainstream media began sounding dire warnings about Testosterone Replacement Therapy (TRT). A recent study was published by the non-profit journal, PLOS One, claiming that in the initial three months of TRT, men were more likely to experience a heart attack if they have previously experienced cardiovascular disease. However, when looked at unemotionally and in detail, the study appears to have overlooked several key factors. This is just one of a barrage of studies that have employed questionable methodologies but used shock value and fear tactics that resulted in hysterical headlines across television, print, and the web. If that weren't enough, a similar study was released last year in the Journal of the American Medical Association (JAMA), which also concluded that Testosterone injections and creams increase the risk of heart attack. That study also had numerous issues which led to faulty conclusions. Let's take a look at them. The Important Relationship of Estrogen and Red Blood Cell Counts to Testosterone Both of the studies mentioned above contained a glaring error: neither study measured Testosterone levels before and after Testosterone treatment. Also, there was yet another huge problem with the methodologies … Read more »

Thanks to Testosterone Replacement Therapy! A skinny, rail-thin man who felt self-conscious about his thin frame has transformed himself from scrawny to brawny, like the “Before/After” photos in the comic book advertisements for muscle-building, mail-order courses...after doctors told him to take testosterone injections. Danny May, 25, from Liverpool, United Kingdom, struggled with his body image for years until he discovered that he suffers from a condition that prevents his body from producing testosterone, the 'male' hormone, naturally. But since he began medically supervised testosterone replacement therapy (TRT), the bartender who was once mistaken for a child by a waitress has become a bodybuilder with a commanding presence that lets people know without asking what he does in his spare time: hit the weights. Danny had suffered as a result of his body image throughout school, and always felt significantly smaller than friends and was unable to find a girlfriend because of his boney, scrawny physique. But When He Was 20, He Discovered What His Problem Was He had a condition called Kallmann Syndrome, a rare disease which affects one in 50,000 and means the body doesn't produce testosterone. In essence, he had the body of a pre-pubescent 11-year-old. Fed up … Read more »

Have you been a bit moody lately? Always feeling fatigued? Lacking motivation? Depressed about your lack of sex drive, or inability to perform in the bedroom? Then Maybe That Dreaded “Low-T” Syndrome has Struck Face reality. It may be time to have your testosterone checked. Similar to how vital estrogen is for a woman, an adequate level of testosterone is just as crucial to a man. Testosterone is primarily a male hormone, and men have significantly higher levels of testosterone flowing through their veins than women. When those levels drop (usually due to aging), men feel it, and it's devastating in all critical areas of a man's life: physically, mentally, and emotionally. Here are five things you need to know that will allow you to understand better how this masculine hormone functions, and why you may need to have your testosterone levels checked... Low testosterone is not just a concern of aging men. While it is true that levels begin to decline after about 25-30 years old, low levels can occur at any age. Men in their early 20s and 30s can be at risk for low concentrations, especially if they have type 1 or type 2 diabetes, autoimmune diseases, … Read more »