Testosterone Therapy is highly beneficial for patients suffering from Andropause (Age-Related Low-T).
Unfortunately, some individuals can't take Testosterone for medical reasons.
Men with prostate cancer, for example, have long been advised not to take Bio-Identical Testosterone because the treatment could feed and exacerbate the spread of cancerous tissue.
It's long been believed that Testosterone could induce the rapid spread of Prostate Cancer, but this may not always be the case.
New studies are engaging this long-held belief. A recent study reports that some men with metastatic prostate cancer or biochemical recurrence may still use Testosterone Therapy.
This is the first study of its kind, which reports that Low-T Treatment may be an option for a subset of these patients.
Dr. Abraham Morgentaler was the lead researcher for this study conducted on behalf of Harvard Medical School's Beth Israel Deaconess Medical Center. The study was released in the medical journal Androgens: Clinical Research and Therapeutics.
This journal is highly respected and showcases research that involves the use of Testosterone Therapy and other Androgenic medical treatments.
Metastatic vs. Primary Prostate Cancer and Biochemical Recurrence
Metastatic Prostate Cancer refers to cancer that has spread beyond the prostate to other organs. Primary Prostate Cancer is the term for cancer that has not spread beyond the prostate.
Biochemical recurrence refers to an increase in Prostate-Specific Antigen activity after successful Prostate Cancer treatment that can sometimes mean that Prostate Cancer has returned.
The doctor and his associates collected data from patients treated with Testosterone Therapy who had a prostate cancer history. Twenty-two men were evaluated in this study. Specifically, three groups of patients were analyzed:
- Patients treated with Androgen-Suppressing Hormones during Primary Prostate cancer Treatment (2 Patients)
- Men with Metastatic Prostate Cancer (13 patients)
- Patients Diagnosed with Biochemical Recurrence (7 patients)
Prostate Cancer Patients Taking Testosterone
These men all received Testosterone HRT between 2005 and June of 2020 at Men's Health Boston. Men that experienced Biochemical Recurrence had PSA Levels checked every three months for a year and semiannually after the first year.
These patients underwent imaging every six months. Patients with Metastatic Prostate Cancer had Prostate-Specific Antigen Levels tested every three months and went for imaging every six months.
Most of the men treated experienced no progression of Prostate Cancer.
All three groups experienced an increase in PSA Levels, though men that underwent Androgen Deprivation experienced the smallest increase (0.1 to 0.3 ng/mL). Metastatic Patients went from 6.3 to 17.8ng/mL, and Biochemical Recurrence patients progressed from 3.1 to 13.3 ng/mL.
During the period of study, three patients died, one of which died of prostate cancer. None of the men with Biochemical Recurrence died, and only one experienced metastasis over the course of 16 months of Bio-Identical Testosterone. Four of the seven men continued using Testosterone, and none of the others experienced complications.
Men with Metastatic Prostate Cancer fared worse, with a 21.4% mortality, 7.1% of which was due to prostate cancer. Ten of the 13 patients in this group underwent imaging for a year after initiating Low-T Treatment.
Seven patients did not see their cancer spread, while three had cancer spread to new bone tissue. Patients experienced several complications, including one heart attack, bone marrow replacement, deep vein thrombosis, and urosepsis.
Six patients kept taking Testosterone out of the eleven that survived the duration of the study.
Androgen Suppressed Patients Experienced No Issues with Low-T Treatment
The two patients that received Androgen Deprivation Therapy experienced no major issues during treatment. One used Testosterone only for a year, while the other stayed on Hormone Replacement, combining Testosterone with Enzalutamide.
Also known as Xtandi, Testosterone, and Enzalutamide are prescribed in alternating fashion to allow the patient to experience the benefits of Testosterone while minimizing the risk of exacerbating prostate cancer.
Could Some Prostate Cancer Patients Take Testosterone Safely?
The goal of this Testosterone/Prostate Cancer study is not to advocate that all Prostate Cancer Patients should take Testosterone but to question the collective wisdom that Testosterone Therapy is inevitably very dangerous for Prostate Cancer Patients.
While this research is obviously preliminary, it opens the door for larger and more diverse studies comparing how various expressions of Prostate Cancer respond to Testosterone Therapy.
The last generation of research has shown that Testosterone is critical to men's health, and it's important to explore how Testosterone HRT may be able to benefit some patients with primary Prostate Cancer or those that may have low-risk prostate cancer in the future.
Androgen Deprivation Therapy is the go-to treatment for patients with metastatic prostate cancer and biochemical recurrence. Dr. Morgentaler believes that for some of these patients, especially those with biochemical recurrence and those on Androgen Deprivation, Testosterone Therapy may be well worth the risk.
Testosterone Deficiency leads to many dangerous symptoms, increases mortality risk, and reduces the quality of life, including low libido, osteoporosis, depression, increased body fat, loss of muscle mass, fatigue, and erectile dysfunction.
It's likely that some patients that have prostate cancer or a history of the disease can still benefit from Testosterone Therapy.
Contact Us Today For A Free Consultation
- Are All HRT Clinics the Same? - April 30th, 2023 [April 21st, 2023]
- Avatar director James Cameron says testosterone is toxic. Commentators on Twitter call him a 'beta male' - December 6th, 2022 [December 6th, 2022]
- Two Food Compounds can reduce Alzheimer's Risk! - January 16th, 2023 [December 1st, 2022]
- Blue Zones Ground Zero of Longevity - November 12th, 2022 [November 8th, 2022]
- Tongkat Ali - Does this Testosterone Boosting Herbal Supplement Actually Work? - October 27th, 2022 [October 27th, 2022]
- Male menopause: it’s real! - December 16th, 2022 [October 26th, 2022]
- Recent Poll concludes: Sexual health is a big concern for men - January 2nd, 2023 [October 5th, 2022]
- Testosterone Impacts Behavior Based on Social Context—An Animal Study - October 7th, 2022 [September 25th, 2022]
- Testosterone Lowers Insulin Resistance in Obese Men - January 16th, 2023 [September 25th, 2022]
- Could Low-T Affect Employment Status? - September 9th, 2022 [September 1st, 2022]
- Keto Diet for Weight Loss and Low-T Relief - December 31st, 2022 [August 2nd, 2022]
- Tlando Oral Testosterone - A Pill for Low-T - June 24th, 2022 [June 14th, 2022]
- The Importance of Follicle-Stimulating Hormone for Men - June 24th, 2022 [February 10th, 2022]
- Jatenzo Testosterone Oral Treatment for Low Testosterone - June 24th, 2022 [December 16th, 2021]
- Testosterone Increases Tenacity and Persistence In Spite of Long Odds - May 17th, 2023 [November 27th, 2021]
- The Impact of Diet on Testosterone - Investigating the Science - November 26th, 2021 [November 9th, 2021]
- Investigating the Effects of Weed on Testosterone Levels and Sexual Health - November 17th, 2021 [October 30th, 2021]
- Improve Sexual Health and Testosterone Levels By Adopting the Mediterranean Diet - November 27th, 2021 [October 2nd, 2021]
- Testosterone Boosting Foods - Food Science Explored - November 27th, 2021 [September 9th, 2021]
- Alaska Testosterone Clinics for Low-T and Hormone Therapy - October 18th, 2021 [September 8th, 2021]
- Fracking Pollution Potential Danger to Testosterone Levels - November 2nd, 2021 [September 8th, 2021]
- Increase Longevity and Live Healthier with the Help of These Supplements - October 18th, 2021 [August 6th, 2021]
- What Doctors Think You Should Understand About Testosterone - November 29th, 2021 [July 1st, 2021]
- Eleven Year Study Showcases Benefits of Testosterone Therapy for Weight Loss - November 12th, 2021 [June 24th, 2021]
- Men With Low-T at Greater Risk of Deadly Covid-19 Complications - November 11th, 2021 [June 3rd, 2021]
- Combining Exercise with Testosterone Therapy for Better Results - November 16th, 2021 [May 28th, 2021]
- Exercise Enhances the Benefits of Testosterone Replacement Therapy - November 19th, 2021 [May 13th, 2021]
- Premature Ejaculation More Common Than You Think - October 29th, 2021 [May 6th, 2021]
- Pro-Inflammatory Diet May Significantly Increase Low-T Risk - November 16th, 2021 [April 29th, 2021]
- Testosterone Replacement Therapy provides heart protection - April 15th, 2021 [April 15th, 2021]
- Six Hacks to Naturally Boost Testosterone Production - November 19th, 2021 [April 14th, 2021]
- The Effects of Parenthood on Testosterone Levels in Men - November 6th, 2021 [April 8th, 2021]
- The Effects of Masturbation on Sex Drive and Testosterone - November 21st, 2021 [April 8th, 2021]
- Study Explores the Effects of Testosterone on Generosity - November 18th, 2021 [April 4th, 2021]
- Over exertion in Endurance Training Can Lower Testosterone - November 18th, 2021 [March 22nd, 2021]
- Primary vs. Secondary Hypogonadism in Men - November 1st, 2021 [March 15th, 2021]
- Covid-19 May Impair Testosterone Levels - October 16th, 2021 [March 9th, 2021]
- Boosting Testosterone Levels and Enhancing Wellness Without Prescriptions and Supplements - October 21st, 2021 [March 5th, 2021]
- Building Muscle, Burning Fat, and Busting Myths - November 6th, 2021 [March 5th, 2021]
- Anakinra May Improve Testosterone Levels in Patients with Metabolic Syndrome - November 27th, 2021 [March 3rd, 2021]
- FDA Approves Jatenzo Oral Testosterone Replacement for Certain Types of Hypogonadism - October 17th, 2021 [February 24th, 2021]
- Vitamin D and Sunlight for Mood and Hormone Balance - October 24th, 2021 [February 22nd, 2021]
- Montana Testosterone Clinics for Low-T and Hormone Therapy - November 3rd, 2021 [February 21st, 2021]
- South Dakota Testosterone Clinics for Low-T and Hormone Therapy - November 1st, 2021 [February 19th, 2021]
- Hormone Levels and Smoking -- What You Can Do to Stop Smoking for Good! - November 12th, 2021 [February 17th, 2021]
- Maine Testosterone Clinics for Low-T and Hormone Therapy - October 24th, 2021 [February 16th, 2021]
- Poor Sleeping Habits Tied to Low-T, Erectile Dysfunction, and Increased Mortality Risk - November 17th, 2021 [February 12th, 2021]
- Minnesota Testosterone Clinics for Low-T and Hormone Therapy - November 12th, 2021 [February 10th, 2021]
- Oklahoma Testosterone Clinics for Low-T and Hormone Therapy - November 27th, 2021 [February 9th, 2021]
- The Effect of Success on Testosterone Levels and Romantic Self-Perception - November 1st, 2021 [February 8th, 2021]
- Wyoming Testosterone Clinics for Low-T and Hormone Therapy - November 23rd, 2021 [February 7th, 2021]
- "Mano-pause" AKA Male Menopause or Andropause, and the Treatment of Age-Related Low-T / Low Testosterone / Hypogonadism - November 6th, 2021 [February 7th, 2021]
- Mississippi Testosterone Clinics for Low-T and Hormone Therapy - November 6th, 2021 [February 6th, 2021]
- Hawaii Testosterone Clinics for Low-T and Hormone Therapy - October 31st, 2021 [February 4th, 2021]
- Dallas Texas Testosterone Clinics for Bio-Identical Testosterone Replacement Therapy - October 26th, 2021 [February 3rd, 2021]
- Massachusetts Testosterone Clinics for Low-T and Hormone Therapy - November 23rd, 2021 [January 29th, 2021]
- New Mexico Testosterone Clinics for Low-T and Hormone Therapy - November 20th, 2021 [January 27th, 2021]
- Nevada Testosterone Clinics for Low-T and Hormone Therapy - October 19th, 2021 [January 24th, 2021]
- Delaware Testosterone Clinics for Low-T and Hormone Therapy - November 20th, 2021 [January 23rd, 2021]
- The Four Best Ways to Amplify Testosterone Levels - November 15th, 2021 [January 21st, 2021]
- Arkansas Testosterone Clinics for Low-T and Hormone Therapy - November 29th, 2021 [January 18th, 2021]
- Arizona Testosterone Clinics for Low-T and Hormone Therapy - November 15th, 2021 [January 14th, 2021]
- Precursor Fat Cells and Their Potential Role in Obesity - October 18th, 2021 [December 30th, 2020]
- Xyosted Self-Administered Testosterone Therapy FDA-Approved - November 7th, 2021 [December 23rd, 2020]
- Testosterone Therapy Reduces Mortality Risk Among Diabetics Even When Accounting for Improvements in Cardiovascular Risk Factors - November 28th, 2021 [December 16th, 2020]
- Male Fertility Myths and Misunderstandings Resolved - October 31st, 2021 [December 15th, 2020]
- The Effects of Testosterone Among Healthy Men and Men With Low-T - November 13th, 2021 [December 14th, 2020]
- San Francisco Testosterone Clinics for Bio-Identical Testosterone Replacement Therapy - November 29th, 2021 [December 9th, 2020]
- Low-T Strongly Associated with Various Co-Morbid Medical Conditions - November 19th, 2021 [December 4th, 2020]
- Natesto: FDA-Approved Nasal Testosterone Gel - November 16th, 2021 [December 1st, 2020]
- New Hampshire Testosterone Clinics for Low-T and Hormone Therapy - October 19th, 2021 [November 29th, 2020]
- Wisconsin Testosterone Clinics for Low-T and Hormone Therapy - October 29th, 2021 [November 25th, 2020]
- Connecticut Testosterone Clinics for Low-T and Hormone Therapy - November 18th, 2021 [November 24th, 2020]
- Scientific Debate Over Testosterone Replacement Therapy for Low-T Continues - November 3rd, 2021 [November 16th, 2020]
- Some Women May Benefit from Testosterone for Menopause - October 29th, 2021 [November 14th, 2020]
- Sioux Falls Testosterone Clinics for Low-T and Comprehensive Hormone Therapy - October 26th, 2021 [November 11th, 2020]
- Chattanooga Testosterone Clinics for Low-T and Comprehensive Hormone Therapy - October 23rd, 2021 [November 11th, 2020]
- Clarksville Testosterone Clinics for Low-T and Comprehensive Hormone Therapy - November 5th, 2021 [November 11th, 2020]
- Knoxville Testosterone Clinics for Low-T and Comprehensive Hormone Therapy - November 21st, 2021 [November 11th, 2020]
- Memphis Testosterone Clinics for Low-T and Comprehensive Hormone Therapy - November 14th, 2021 [November 11th, 2020]
Word Count: 849