What is Testosterone?
Testosterone is one of the many chemical messengers known as Hormones, and it is essential for the usual health and function of both men and women. However, the hormone is primarily associated with male wellness and development.
Testosterone belongs to a specific class of hormones known as steroids. Most people think of steroids as hormones or chemicals that boost anabolic, muscle-building performance. Still, a steroid represents a molecule with a specific structure that is most commonly used to deliver messages and exert physiological changes in the body.
Three common steroids are cholesterol, testosterone, and estrogen. In fact, the human body builds both Testosterone and Estrogen from a core of cholesterol, which is one reason why cholesterol is such an essential part of daily nutritional intake.
Testosterone and Prenatal Development
Testosterone is responsible for the development of primary male sex characteristics while the child is still in the womb. In the normal developmental cycle, Testosterone begins to affect the male fetus around seven weeks after conception. It encourages the formation of Leydig Cells, which are responsible for the production of Testosterone.
After the fetus develops its own ability to produce Testosterone, the internal male sexual organs begin to grow, and at around eight weeks, external sexual organs begin to develop fully.
Testosterone and Puberty
After primary sex characteristics are established, the influence of Testosterone diminishes almost completely until puberty, where Testosterone triggers the development of secondary sex characteristics.
Testosterone also triggers muscle development and growth. Human Growth Hormone is also responsible for growth, and the combination of Testosterone and Human Growth Hormone during puberty is why men grow taller than women.
When puberty begins, the hypothalamus starts to release the ultimate precursor hormone of Testosterone: Gonadotropin-Releasing Hormone, or GnRH. GnRH travels from the hypothalamus to the pituitary gland where the production of Follicle-Stimulating Hormone and Luteinizing Hormone begin, which are responsible for the production of sperm and testosterone, respectively.
Testosterone Levels in the bloodstream are mediated by a negative feedback loop. As serum Testosterone Levels increase, a small amount of Testosterone is converted into Estrogen, primarily by body fat, which then circulates to the hypothalamus and suppresses the production of Testosterone precursors.
Anabolic Actions of Testosterone
Testosterone is a hormone that encourages growth and development. During puberty, the male physiologically changes significantly. He begins to put on muscle mass, and this triggers a reduction in body fat. Testosterone amplifies the growth spurt induced by Human Growth Hormone, and also eventually leads to the closure of the epiphysial plates, which concludes the growth spurt.
The vocal cords get thicker, and the larynx grows, which leads to the deepening of the voice associated with male puberty. Finally, Testosterone encourages the full development and functionality of the male sex organs, and the testicles start to produce sperm.
The Influence of Testosterone During Adulthood
Beyond puberty, Testosterone Levels normalize, and no longer have a significant impact on the structure of the male body, except when Testosterone Levels become deficient.
Testosterone ultimately becomes an agent of homeostasis, helping the male body retain its health and potency. Testosterone contributes heavily to the ability to form an erection and produce sperm, and it also sustains muscle mass and body fat distribution. Testosterone also appears to have protective effects upon many systems in the body.
For example, there is convincing evidence that men that don't produce enough Testosterone are more likely to suffer from depression, anxiety, and even cognitive decline and Alzheimer's disease.
How Is Testosterone Found in the Body?
Natural Testosterone exists in the bloodstream in three different forms. Some Testosterone circulates through the body without being attached to any other molecule—This Testosterone is referred to as Unbound Testosterone.
Testosterone is also found flowing through the bloodstream attached to Sex hormone-binding Globulin, which stores Testosterone and cannot be used by the body while bound. A third form of Testosterone in the bloodstream is attached to Albumin. Unlike with SHBG, Albumin has a weak binding with Testosterone, and this Testosterone can still be made available to the body.
Most circulating Testosterone is attached to SHBG, meaning that most Testosterone in the bloodstream cannot be actively used by the body. If a person produces too much SHBG, this reduces the effectiveness of Testosterone released by the Leydig Cells and contributes to Testosterone Deficiency.
There are many factors that can lead to increased SHBG, including overactive thyroid, abnormally high estrogen levels, and natural aging.
Testosterone that travels through the bloodstream can be used by the body to make other vital hormones. For example, 5-alpha reductase is an enzyme that converts Testosterone into Dihydrotestosterone, also known as DHT.
Elevated DHT levels are associated with an enlarged prostate because DHT stimulates the reproduction of prostate cells. Testosterone also encourages the production of Estrogen via adipose fat tissue, and elevated Estrogen levels are the primary mechanism by which Testosterone production is controlled via the hypothalamus.
How Do Testosterone Levels Change as a Function of Age?
Testosterone Levels are vitally crucial to male (and to a lesser extent, female) homeostasis. Testosterone Production remains steady through the late teens and the twenties and starts to enter a steady decline starting at age thirty. This decline actually begins around thirty for both sexes.
Testosterone Secretion slows gradually, at a rate of about one percent annually. After many years, however, this decline can begin to produce symptoms associated with hormone imbalance, such as weight gain, fatigue, loss of muscle mass, depression, anxiety, cognitive decline, loss of bone mineral density, erectile dysfunction, and loss of libido.
Age-related Testosterone Decline is often referred to as Andropause because it manifests around the same age as Menopause in many men.
On the other hand, Testosterone is a slow drop in Testosterone Production, and Testosterone Production does not cease wholly and suddenly, as is the case with Estrogen and Menopause. Testosterone Deficiency can inhibit fertility when severe, but most men retain some fertility even in the case of significant deficiency.
For men with Testosterone Deficiency, Testosterone Therapy with Testosterone Injections, Testosterone Patches, or Testosterone Creams can help restore Hormonal Homeostasis and counteract many of the symptoms of abnormally low Testosterone Levels.
- What is testosterone? - May 23rd, 2021
- Tribulus Terrestris Review Does It Raise Testosterone or ... - May 22nd, 2021
- Boosting testosterone levels (First of two parts) - May 8th, 2021
- How long does it take for Testosterone replacement treatments and therapy to work? - May 1st, 2021
- What Is Testosterone AndroGel - April 28th, 2021
- Low T - My life was falling apart because I had low testosterone - April 25th, 2021
- Deer Antler, HGH and Testosterone: Tim on Scott and BR Radio Show - Video - April 17th, 2021
- What is Testosterone? What does Testosterone do? Find on - April 14th, 2021
- How Testosterone Affects the Skin of Men - April 11th, 2021
- Testosterone, the Power Hormone - April 8th, 2021
- Testosterone Levels and Wall Street - March 27th, 2021
- Women can resist testosterone-fuelled political debate - March 12th, 2021
- BUSTED: Myths About Testosterone And Its Link To Sexual Desire In Men And Women - March 11th, 2021
- Baby Boomers find “The Fountain of Youth” in Testosterone - March 4th, 2021
- Declining Testosterone Levels in Men Not Part of Normal Aging - February 28th, 2021
- Quick Weight Loss Tips and Diet Recommendations for HRT - February 28th, 2021
- Testosterone and Alcohol: Your Health and the Holiday Season - February 27th, 2021
- Testosterone builds muscle but has risks - February 25th, 2021
- New Study Finds That Testosterone Does Not Increase Cardiovascular Risk - February 22nd, 2021
- Evidence Suggests Testosterone Plays Powerful Role in Motivating Revolutionary Change - February 15th, 2021
- The Effects of Parenthood Upon Testosterone Levels - January 9th, 2021
- Testicular Cancer Survivors are at Risk for Low Testosterone - January 6th, 2021
- Amygdala and it's Relationship to Testosterone and Fear - December 25th, 2020
- Testosterone Does Not Cause Atherosclerosis (Hardening of the Arteries) in Older Men - December 24th, 2020
- Increased Testosterone DOES NOT Cause Prostate Cancer to Spread - December 23rd, 2020
- Testosterone Cypionate and Testosterone Enanthate: The Real Facts - December 20th, 2020
- A Surprising Side Effect of Methadone Treatment: Suppressed Testosterone - December 18th, 2020
- The Testosterone Industry Globally is Booming - December 12th, 2020
- Five Benefits of Testosterone That You Need to Know - December 11th, 2020
- Testosterone Nasal Gel: A New Form of Testosterone Replacement Therapy - December 5th, 2020
- New Research Proves Testosterone Replacement Therapy is Safe for the Heart - December 3rd, 2020
- Skinny Bartender with Low Testosterone Becomes a Ripped Bodybuilder - December 3rd, 2020
- Low-T and Your Health - November 30th, 2020
- Low Testosterone Levels may Affect Man's Sex Drive and Affect his Intimate Relationships - November 19th, 2020
- Is Testosterone the New Drug of Choice on Wall Street? How Traders are Using Male Hormone Booster Shots to Maintain a ... - November 12th, 2020
- Shorter course of ADT for high-risk prostate cancer patients yields improved quality of life - November 11th, 2020
- Testosterone Litigation: What You Need To Know - MTMP - Video - November 9th, 2020
- Methadone Lowers Testosterone in Men Only - November 8th, 2020
- Intricate relationship between Oestrogen & Testosterone XXY Guys (Klinefelters' syndrome) - Video - November 7th, 2020
- Should middle-aged men consider 'low T' treatment? - November 5th, 2020
- Testosterone and Crime: What Can Genes Tell Us About Behavior? - Video - October 25th, 2020
- Testosterone shown to help sexually frustrated women - October 22nd, 2020
- Testosterone levels seen prior to birth in fetus' fingers, jawline - October 20th, 2020
- Tri-Blend Testosterone. Understanding the Benefits of Testosterone Oils - October 19th, 2020
- Testosterone levels in older men - October 17th, 2020
- Tlando Testosterone Clinical Trial for Low-T and Fatty Liver Disease - October 4th, 2020
- Testosterone Focus in Diabetes Study – Video - September 30th, 2020
- Testshock Review All Natural Testosterone Enhancement – Video - September 30th, 2020
- Testosterone, Anxiety, and Depression - September 30th, 2020
- Average Testosterone Levels Decreasing Over Time Among Younger American Men - August 21st, 2020
- Testosterone Creams for Low Testosterone Treatment and Andropause - August 10th, 2020
- Testosterone Therapy and Androgen Deficiency Guide - August 6th, 2020
- Testosterone's Surprising Link to Men's 'Love Hormone' Oxytocin - August 5th, 2020
- Fortesta Brand Testosterone Therapy - August 3rd, 2020
- Andropause: Age-Associated Testosterone Decline - August 1st, 2020
- How to Build Muscle Quickly by Boosting Testosterone Levels - July 29th, 2020
- Testosterone Deficiency Strongly Linked to Heart Attack Risk in New Study - July 26th, 2020
- Seven Types of Drugs That Can Inhibit Sex Drive and Libido - July 22nd, 2020
- Testosterone and Geriatric Frailty - July 21st, 2020
- Testosterone and Aggression: How T-Levels Impact Human Response to External, Social Threats - July 12th, 2020
- High-Dose Testosterone Injections May Be a Viable Palliative Late-Stage Prostate Cancer Treatment - July 12th, 2020
- Could Civilization Have Been Formed as a Result of Declining Testosterone Levels in Males? - July 6th, 2020
- Testosterone Therapy Allows Man to Have the Body That He Was Meant to Have - July 5th, 2020
- Testosterone Injections for Low-T and Andropause - July 4th, 2020
- Testosterone Replacement Therapy (TRT) Reduces the Risk of Serious Adverse Health Consequences! - June 30th, 2020
- More Sex: A Better Way to Boost Your Testosterone Levels - June 29th, 2020
- Testosterone not always to blame - Sat, 04 Aug 2012 PST - June 28th, 2020
- Five Facts About Testosterone (That Maybe You Didn't Know) - June 27th, 2020
- Manhood Washed Away: You Could Unknowingly be Annihilating Your Testosterone - June 23rd, 2020
- Testosterone: Should You Take it to Regain Your Libido and Youthful Energy? - June 22nd, 2020
- Testosterone Replacement Therapy Boosts Aerobic Capacity - June 15th, 2020
- The Truth Behind Common Male Sex Myths - May 26th, 2020
- Dr. Andre Berger on Testosterone Deficiency in Men - Andropause Symptoms and Treatment By Doctor's Desk Series - May 21st, 2020
- How to Raise Testosterone Naturally. Sermorelin - Some Have Called It A The New Fountain of Youth. A Natural Cure for Anxiety and Depression. - May 9th, 2020
- Are Athletes Using Green Tea to Mask Testosterone Doping? - May 7th, 2020
- Some Animal Research Suggests that High Testosterone May Increase Prostate Cancer Risk - May 5th, 2020
- Eleven Foods that Can Drain Your Libido - May 4th, 2020
- Testosterone Can Make Us Generous, But Only When We Do Not Perceive a Threat - May 3rd, 2020
- A New Link Between Testosterone and the Prevention of Dementia in Women - May 3rd, 2020
- Why Women Make Better Money Managers - April 30th, 2020
Word Count: 1038