What is Testosterone?
Testosterone is one of the many chemical messengers known as Hormones, and it is important for the normal health and function of both men and women, though the hormone is primarily associated with male wellness and development. Testosterone belongs to a specific class of hormones known as steroids. Most people think of steroids as hormones or chemicals that boost anabolic, muscle-building performance, but a steroid represents a molecule with a specific structure that is most commonly used in order to deliver messages and exert physiological changes in the body.
Three common steroids are cholesterol, testosterone, and estrogen. In fact, the human body builds both Testosterone and Estrogen from a core of cholesterol, which is one reason why cholesterol is such an important part of daily nutritional intake.
Testosterone and Prenatal Development
Testosterone is responsible for the development of primary male sex characteristics while the child is still in the womb. In the normal developmental cycle, Testosterone begins to affect the male fetus around seven weeks after conception, and encourages the formation of Leydig Cells, which are responsible for the production of Testosterone. After the fetus develops its own ability to produce Testosterone, the internal male sexual organs begin to develop, and at around eight weeks, external sexual organs begin to develop fully.
Testosterone and Puberty
After primary sex characteristics are established, the influence of Testosterone diminishes almost completely until puberty, where Testosterone triggers the development of secondary sex characteristics. Testosterone also triggers muscle development and growth. Human Growth Hormone is also responsible for growth, and the combination of Testosterone and Human Growth Hormone during puberty is why men grow taller than women.
When puberty begins, the hypothalamus starts to release the ultimate precursor hormone of Testosterone: Gonadotropin-Releasing Hormone, or GnRH. GnRH travels from the hypothalamus to the pituitary gland where the production of Follicle-Stimulating Hormone and Luteinizing Hormone begin, which are responsible for the production of sperm and Testosterone, respectively.
Testosterone Levels in the blood stream are mediated by a negative feedback loop. As serum Testosterone Levels increase, a small amount of Testosterone is converted into Estrogen, primarily by body fat, which then circulates to the hypothalamus and suppresses the production of Testosterone precursors.
Anabolic Actions of Testosterone
Testosterone is a hormone which encourages growth and development. During puberty, the male physiologically changes significantly. He begins to put on muscle mass and this triggers a reduction in bodyfat. Testosterone amplifies the growth spurt induced by Human Growth Hormone, and also eventually leads to the closure of the epiphysial plates, which concludes the growth spurt. The vocal cords get thicker and the larynx grows, which leads to the deepening of the voice associated with male puberty. Finally, Testosterone encourages the full development and functionality of the male sex organs, and the testicles start to produce sperm.
The Influence of Testosterone During Adulthood
Beyond puberty, Testosterone Levels normalize, and no longer have a major impact on the structure of the male body, except when Testosterone Levels become deficient. Testosterone ultimately becomes an agent of homeostasis, helping the male body retain its health and potency. Testosterone contributes heavily to the ability to form an erection and produce sperm, and it also sustains muscle mass and bodyfat distribution. Testosterone also appears to have protective effects upon many systems in the body. For example, there is powerful evidence that men that don't produce enough Testosterone are more likely to suffer from depression, anxiety, and even cognitive decline and Alzheimer's disease.
How Is Testosterone Found in the Body?
Natural Testosterone exists in the bloodstream in three different forms. Some Testosterone circulates through the body without being attached to any other molecule—This Testosterone is referred to as Unbound Testosterone. Testosterone is also found circulating through the bloodstream attached to Sex Hormone-Binding Globulin, which stores Testosterone and cannot be used by the body while bound. A third form of Testosterone in the blood stream is attached to Albumin. Unlike with SHBG, Albumin has a weak binding with Testosterone, and this Testosterone can still be made available to the body.
Most circulating Testosterone is attached to SHBG, meaning that most Testosterone in the blood stream cannot be actively used by the body. If a person produces too much SHBG, this reduces the effectiveness of Testosterone released by the Leydig Cells and contributes to Testosterone Deficiency. There are many factors which can lead to increased SHBG, including overactive thyroid, abnormally high estrogen levels, and natural aging.
Testosterone that travels through the bloodstream can be used by the body to make other important hormones. For example, 5-alpha reductase is an enzyme which converts Testosterone into Dihydrotestosterone, also known as DHT. Elevated DHT levels are associated with enlarged prostate, because DHT stimulates the reproduction of prostate cells. Testosterone also encourages the production of Estrogen via adipose fat tissue, and elevated Estrogen levels are the primary mechanism by which Testosterone production is controlled via the hypothalamus.
How Do Testosterone Levels Change as a Function of Age?
Testosterone Levels are vitally important to male (and to a lesser extent, female) homeostasis. Testosterone Production remains steady through the late teens and the twenties, and starts to enter a steady decline starting at age thirty. This decline actually begins around thirty for both sexes. Testosterone Secretion slows almost imperceptibly, at a rate of about one percent annually. After many years, however, this decline can begin to produce symptoms associated with hormone imbalance, such as weight gain, fatigue, loss of muscle mass, depression, anxiety, cognitive decline, loss of bone mineral density, erectile dysfunction, and loss of libido.
Age related Testosterone Decline is often referred to as Andropause, because it manifests around the same age as Menopause in many men. On the other hand, Testosterone is a slow drop in Testosterone Production, and Testosterone Production does not cease suddenly and completely, as is the case with Estrogen and Menopause. Testosterone Deficiency can inhibit fertility when severe, but most men retain some fertility even in the case of significant deficiency. For men with Testosterone Deficiency, Testosterone Therapy with Testosterone Injections, Testosterone Patches, or Testosterone Creams can help restore Hormonal Homeostasis and counteract many of the symptoms of abnormally low Testosterone Levels.
Contact Us Now
- New Study Finds That Testosterone Does Not Increase Cardiovascular Risk - September 2nd, 2019
- Baby Boomers find “The Fountain of Youth” in Testosterone - September 2nd, 2019
- Dr. Richard Bebb - Testosterone, Diabetes and the Metabolic Syndrome - Video - August 21st, 2019
- Declining Testosterone Levels in Men Not Part of Normal Aging - August 12th, 2019
- Low testosterone levels may affect man's sex drive and affect his intimate relationships - August 11th, 2019
- TEFINA: Nasal Spray That Can Increase Female Orgasms - Video - August 10th, 2019
- Quick Weight Loss Tips and Diet Recommendations for HRT - August 10th, 2019
- Testosterone and Alcohol: Your Health and the Holiday Season - August 9th, 2019
- Testosterone builds muscle but has risks - August 4th, 2019
- Testosterone not always to blame - Sat, 04 Aug 2012 PST - August 4th, 2019
- Testosterone, the Power Hormone - August 1st, 2019
- Behavior and Lifestyle Linked to the Effect of Declining Testosterone, Not Necessarily Natural Aging - July 31st, 2019
- BUSTED: Myths About Testosterone And Its Link To Sexual Desire In Men And Women - July 28th, 2019
- Testosterone shown to help sexually frustrated women 0 - July 20th, 2019
- Green tea could mask testosterone doping - July 14th, 2019
- Some experts say testosterone decline is a normal part of aging in men - July 14th, 2019
- The Secret to Guys’ Sex Appeal: Low Stress, High Testosterone, Strong Immunity - July 7th, 2019
- Low on testosterone? No problem - July 7th, 2019
- Testosterone levels seen prior to birth in fetus' fingers, jawline - July 6th, 2019
- Is testosterone the new drug of choice on Wall Street? How traders are using male hormone booster shots to maintain a ... - July 4th, 2019
- The Effects of Parenthood Upon Testosterone Levels - April 22nd, 2019
- Testicular Cancer Survivors are at Risk for Low Testosterone - April 21st, 2019
- Amygdala and it's Relationship to Testosterone and Fear - April 19th, 2019
- Testosterone Does Not Cause Atherosclerosis (Hardening of the Arteries) in Older Men - April 19th, 2019
- Increased Testosterone DOES NOT Cause Prostate Cancer to Spread - April 19th, 2019
- Testosterone Cypionate and Testosterone Enanthate: The Real Facts - April 19th, 2019
- A Surprising Side Effect of Methadone Treatment: Suppressed Testosterone - April 19th, 2019
- Low T - My life was falling apart because I had low testosterone - April 16th, 2019
- Testosterone Replacement Beneficial for Modern Men? - April 2nd, 2019
- What Is Testosterone AndroGel - April 2nd, 2019
- How long does it take for Testosterone replacement treatments and therapy to work? - April 2nd, 2019
- The Testosterone Industry Globally is Booming - April 1st, 2019
- Five Benefits of Testosterone That You Need to Know - March 31st, 2019
- Testosterone Nasal Gel: A New Form of Testosterone Replacement Therapy - March 17th, 2019
- Testosterone: Should You Take it to Regain Your Libido and Youthful Energy? - March 17th, 2019
- Manhood Washed Away: You Could Unknowingly be Annihilating Your Testosterone - March 17th, 2019
- New Research Proves Testosterone Replacement Therapy is Safe for the Heart - March 17th, 2019
- Skinny Bartender with Low Testosterone Becomes a Ripped Bodybuilder - March 16th, 2019
- Five Facts About Testosterone (That Maybe You Didn't Know) - March 16th, 2019
- Testosterone's Surprising Link to Men's 'Love Hormone' Oxytocin - March 16th, 2019
- More Sex: A Better Way to Boost Your Testosterone Levels - March 15th, 2019
- Testosterone Replacement Therapy Boosts Aerobic Capacity - March 15th, 2019
- Testosterone Replacement Therapy (TRT) Reduces the Risk of Serious Adverse Health Consequences! - March 15th, 2019
- Eleven Foods that Can Drain Your Libido - September 6th, 2018
- Some Animal Research Suggests that High Testosterone May Increase Prostate Cancer Risk - September 6th, 2018
- The Truth Behind Common Male Sex Myths - August 27th, 2018
- Testosterone Injections for Low-T and Andropause - August 26th, 2018
- Testosterone Therapy Allows Man to Have the Body That He Was Meant to Have - August 26th, 2018
- Could Civilization Have Been Formed as a Result of Declining Testosterone Levels in Males? - August 26th, 2018
- Testosterone and Aggression: How T-Levels Impact Human Response to External, Social Threats - August 21st, 2018
- Testosterone Deficiency Strongly Linked to Heart Attack Risk in New Study - August 19th, 2018
- Testosterone and Geriatric Frailty - August 18th, 2018
- Seven Types of Drugs That Can Inhibit Sex Drive and Libido - August 18th, 2018
- Low-T and Your Health - August 17th, 2018
- How to Build Muscle Quickly by Boosting Testosterone Levels - August 9th, 2018
- Andropause: Age-Associated Testosterone Decline - August 5th, 2018
- High-Dose Testosterone Injections May Be a Viable Palliative Late-Stage Prostate Cancer Treatment - August 5th, 2018
- Fortesta Brand Testosterone Therapy - August 3rd, 2018
- Testosterone Therapy and Androgen Deficiency Guide - August 2nd, 2018
- Testosterone Creams for Low Testosterone Treatment and Andropause - August 1st, 2018
- Testosterone, Anxiety, and Depression - July 9th, 2018
- Oral Testosterone Pill Could Make Lipocine's Share Price SKYROCKET - March 18th, 2017
- What is Testosterone? What does Testosterone do? Find on - August 9th, 2016
- The Truth About Testosterone | The Dr. Oz Show - June 9th, 2016
- How Men Work | HowStuffWorks - May 28th, 2016
- 6 Ways to Increase Testosterone Levels Naturally - wikiHow - May 4th, 2016
- Testosterone: Common Questions | Testosterone Test: Total ... - May 4th, 2016
- Adrenalast Testosterone Booster | Boost Muscle Sexual ... - April 6th, 2016
- How to Lower Testosterone in Women | eHow - February 8th, 2016
- Testosterone Booster Reviews - Consumers Guides - February 8th, 2016
- A Harvard expert shares his thoughts on testosterone ... - February 8th, 2016
- Does Andro 400 Work; does it increase testosterone? - February 8th, 2016
- All About Testosterone! - Bodybuilding.com - February 8th, 2016
- 5 Natural Testosterone Boosters - Healthline - November 2nd, 2015
- Testosterone - Low-T and Androgen Replacement Therapy - November 2nd, 2015
- Effect of vitamin D supplementation on testosterone levels ... - October 17th, 2015
- Testosterone nasal gel works best at three doses a day, study finds - October 4th, 2015
- Testosterone: The Test | Testosterone Test: Total ... - October 1st, 2015
- Testosterone: A Major Breakthrough for Menopausal Women - October 1st, 2015
- Testosterone (film) - Wikipedia, the free encyclopedia - October 1st, 2015
Word Count: 1045