There has been a lot of debate over the last decade regarding the effects of both Low-T and Testosterone Deficiency on the heart. Depending on the study and the manner in which the study was conducted, the results can come out quite differently.
A study published in Heart Rhythm, a peer-reviewed medical journal regarding cardiovascular health, provides strong evidence that a patient's Estradiol and Testosterone Levels are powerful indicators for sudden cardiac arrest, a lethal condition with a 95% mortality rate.
What researchers found was that men that experienced cardiac arrest had average Testosterone Levels which were significantly lower than normal. It was also discovered that patients with elevated Estradiol Levels were more likely to experience cardiac arrest regardless of gender.
What is Cardiac Arrest?
Cardiac Arrest is a condition in which the heart loses the ability to contract normally, which completely restricts blood flow. This prevents the body from circulating oxygen through the bloodstream which quickly leads to death if not treated.
Sudden Cardiac Arrest refers to Cardiac Arrest which occurs without warning. Because of the severity of the condition, under most circumstances, there is no way to provide effective treatment in time to save the patient, nor return the heart to working function in time to save the patient.
Cardiac Arrest as a whole has a lower mortality rate, though is still quite lethal because the condition often occurs in a hospital environment where immediate treatment can be provided. It's important to understand that Cardiac Arrest and Heart Attack are two specific conditions.
Cardiac Arrest vs. Heart Attack
A heart attack is a condition in which blood flow is restricted to the heart, but the muscle is still functional, whereas, in the case of Cardiac Arrest, blood is available for circulation, but the heart is not functioning properly, if at all.
Heart Attacks are referred to as medically and scientifically as Myocardial Infarctions. Both of these conditions are distinct from heart failure, a condition in which the heart is limited in its capacity to encourage healthy circulation but can still support the survival of the patient.
Because of the limited treatment options and the incredibly high mortality rate for Sudden Cardiac Arrest, there is an emphasis on medical research to find ways to reduce the risk of the condition in order to improve the long-term outcomes for at-risk patients.
How Widespread is Sudden Cardiac Arrest?
Sudden Cardiac Arrest is one of the leading killers of Americans and men and women all across the world. As many as 300,000 people die of Sudden Cardiac Arrest in the United States annually, and the number is as high as five million globally.
Why is Cardiac Arrest So Much Worse than Heart Attack?
The majority of heart attacks happen because the Coronary Artery becomes so blocked that blood cannot adequately reach the heart. In many cases, this is not a total blockage, although in some cases, such as in the case of clotting, this blockage can become total.
Because Heart Attacks don't always lead to total blockages, the patient can frequently survive long enough to receive treatment, because there is just enough blood circulation to keep them going. On the other hand, Cardiac Arrest completely stalls blood circulation, which must be treated in a matter of minutes before organ death starts to take place rapidly.
Also, Sudden Cardiac Arrest is a more complex issue than a heart attack. A heart attack is like having a fuel pump with a clog in it. If you can flush the tube and free the blockage, the engine will still function normally as fuel returns to circulation.
On the other hand, Sudden Cardiac Arrest is a problem with electrical signaling, and, outside of a clinical setting, or the lack of a defibrillator, blood circulation completely stops with no recourse.
Despite Decades of Research, Cardiac Arrest is Still Extremely Lethal
Generations of medical research have gone into trying to discover a means by which to effectively treat and resuscitate patients that experience sudden cardiac arrest, but survival rates are still particularly grim.
For patients with known heart issues, the best way to protect against cardiac arrest is with an ICD or implantable cardioverter-defibrillator. This device constantly monitors the heart, making sure that it sends electrical signals in its normal pattern. If something happens in which the heart falls out of pattern or goes into cardiac arrest, the ICD shocks the heart to restore normal rhythm patterns.
Using Medical Records to Uncover Cardiac Arrest Risk Factors
Researchers were able to come to these conclusions regarding Testosterone, Estradiol, and Sudden Cardiac Arrest by analyzing data collected from the Oregon Sudden Unexpected Death Study, conducted in Portland, Oregon. The study spanned sixteen hospitals and collected comprehensive data regarding patients that passed unexpectedly.
The study was largely funded by the National Heart, Lung, and Blood Institute, and the research leader was Dr. Sumeet Chugh. By analyzing data collected from patients that died unexpectedly, researchers hoped to uncover genetic defects, triggers, and other risk factors for sudden cardiac arrest and heart death.
Although previous studies have linked Testosterone Deficiency and Elevated Estradiol to increased cardiovascular risk in other ways, this is the first study that provides evidence that abnormal hormone balance is correlated with sudden cardiac arrest.
Although the research needs to be corroborated through future studies, this is strong evidence that Hormone Balance with regard to Testosterone and Estrogen may have a protective effect on the heart which helps to prevent Sudden Cardiac Arrest.
Chugh and his associates accumulated health data from 149 men and women that died of Sudden Cardiac Arrest.
In order to establish control data, they also collected health information from 149 men and women that suffered from Coronary Artery Disease, but did not experience Sudden Cardiac Arrest.
Cardiac Arrest Risk and Testosterone in Men
What they discovered when analyzing the data was that men that died of Cardiac Arrest had average Serum Testosterone Concentration of 44 ng/dl, whereas patients that did not experience Cardiac Arrest had average levels of 54 ng/dl.
Cardiac Arrest Risk and Estradiol in Men
With regard to Estradiol Levels in men, those that died from Cardiac Arrest had Serum Estradiol Concentrations of 68 pg/ml, whereas those that did not experience the fatal condition had estradiol levels of 52 pg/ml.
Cardiac Arrest Risk and Estradiol in Women
The link between Estradiol and Cardiac Arrest Risk was also notable in female patients as well. Women that experienced Cardiac Arrest had Serum Estradiol Levels of 54 pg/ml, and the controls had an average of 36 pg/ml.
What Does This Data Mean?
Based on this data, there is a definite link between Cardiac Arrest Risk and Testosterone Deficiency / Elevated Estradiol Levels. Of course, the evidence does not point out the source of the correlation.
It is equally feasible that conditions associated with Sudden Cardiac Arrest depress levels of Testosterone and increase Estrogen Levels in the bloodstream, and it is also very possible that Low-T and Elevated Estrogen Levels create a cardiovascular environment more conducive to Sudden Cardiac Arrest.
If Testosterone and Estrogen Levels directly contribute to Sudden Cardiac Arrest risk, then Testosterone Replacement Therapy for men and Estrogen Blockers for both sexes may be a means by which to improve cardiovascular outcomes and reduce the risk of Sudden Cardiac Arrest.
In the case that Testosterone Deficiency and Elevated Estrogen Levels are an indicator of Sudden Cardiac Arrest Risk, these levels may provide evidence that helps point future researchers in the right direction to discover further, direct causes of these lethal heart malfunctions.
Further still, Testosterone Therapy or Estrogen Blockers may still protect the heart by protecting against these other more direct causes of heart malfunction.
Could Hormone Therapy Improve Heart Health and Reduce Cardiovascular Risk?
Of course, there are still important questions that have to be more sufficiently answered with regard to Testosterone Therapy's effects upon the cardiovascular system, as well as those of Estrogen Blockers.
For example, some studies have shown that Testosterone Therapy increases the risk of heart attack, especially in the initial months of treatment. Most of these studies, however, suggest that the heart attack risk is caused by an associated increase in Estradiol Levels caused by the Testosterone Therapy itself, or the result of Polycythemia, which increases the risk of blood clotting.
In both of these cases, Testosterone itself still seems to have a protective effect upon cardiovascular function, but it's benefits are suppressed by the effects of Polycythemia and increased Estradiol Levels.
Both of these side-effects can be effectively treated, however, which still provides hope that Testosterone Therapy can be an effective weapon at the disposal of medical doctors in their efforts to protect the hearts of their patients.
Estrogen Blockers can keep Estradiol Levels in check, suppressing the conversion process which causes excess Testosterone from being converted into Estrogen. Polycythemia can also be effectively treated as well, in this case, without medication.
The best treatment to keep Red Blood Cell Count in check is simply blood donation.
Contact Us Today For A Free Consultation
- MOTS-c Therapy To Improve Body Composition - December 11th, 2022
- Punicalagin: A powerful Testosterone Booster - November 24th, 2022
- Blocking Testosterone to Defeat Melanoma - August 11th, 2022
- Stomach Inflammation: Another Ailment That Testosterone Can Stop in its Tracks - August 3rd, 2022
- Study Finds that Testosterone Boosts Memory for Uncontrolled Diabetics - June 24th, 2022
- Causes of Low Libido - Could It Be Low-T? - May 30th, 2022
- The Evolutionary Effects of Testosterone on Human Society - September 20th, 2021
- More Sex: A Better Way to Boost Your Testosterone Levels - September 7th, 2021
- Men Want to Know – Free Testosterone versus Total Testosterone - August 24th, 2021
- What is testosterone? - May 23rd, 2021
- Tribulus Terrestris Review Does It Raise Testosterone or ... - May 22nd, 2021
- Boosting testosterone levels (First of two parts) - May 8th, 2021
- How long does it take for Testosterone replacement treatments and therapy to work? - May 1st, 2021
- What Is Testosterone AndroGel - April 28th, 2021
- Low T - My life was falling apart because I had low testosterone - April 25th, 2021
- Deer Antler, HGH and Testosterone: Tim on Scott and BR Radio Show - Video - April 17th, 2021
- What is Testosterone? What does Testosterone do? Find on - April 14th, 2021
- How Testosterone Affects the Skin of Men - April 11th, 2021
- Testosterone, the Power Hormone - April 8th, 2021
- Testosterone Levels and Wall Street - March 27th, 2021
- Women can resist testosterone-fuelled political debate - March 12th, 2021
- BUSTED: Myths About Testosterone And Its Link To Sexual Desire In Men And Women - March 11th, 2021
- Attention Baby Boomers -- Could Testosterone be the Modern Day "Fountain of Youth?" - March 4th, 2021
- Declining Testosterone Levels in Men Not Part of Normal Aging - February 28th, 2021
- Quick Weight Loss Tips and Diet Recommendations for HRT - February 28th, 2021
- Testosterone and Alcohol: Your Health and the Holiday Season - February 27th, 2021
- Testosterone builds muscle but has risks - February 25th, 2021
- New Study Finds That Testosterone Does Not Increase Cardiovascular Risk - February 22nd, 2021
- Evidence Suggests Testosterone Plays Powerful Role in Motivating Revolutionary Change - February 15th, 2021
- The Effects of Parenthood Upon Testosterone Levels - January 9th, 2021
- Testicular Cancer Survivors are at Risk for Low Testosterone - January 6th, 2021
- Amygdala and it's Relationship to Testosterone and Fear - December 25th, 2020
- Testosterone Does Not Cause Atherosclerosis (Hardening of the Arteries) in Older Men - December 24th, 2020
- Increased Testosterone DOES NOT Cause Prostate Cancer to Spread - December 23rd, 2020
- Testosterone Cypionate and Testosterone Enanthate: The Real Facts - December 20th, 2020
- A Surprising Side Effect of Methadone Treatment: Suppressed Testosterone - December 18th, 2020
- The Testosterone Industry Globally is Booming - December 12th, 2020
- Five Benefits of Testosterone That You Need to Know - December 11th, 2020
- Testosterone Nasal Gel: A New Form of Testosterone Replacement Therapy - December 5th, 2020
- New Research Proves Testosterone Replacement Therapy is Safe for the Heart - December 3rd, 2020
- Skinny Bartender with Low Testosterone Becomes a Ripped Bodybuilder - December 3rd, 2020
- Low-T and Your Health - November 30th, 2020
- Low Testosterone Levels may Affect Man's Sex Drive and Affect his Intimate Relationships - November 19th, 2020
- Is Testosterone the New Drug of Choice on Wall Street? How Traders are Using Male Hormone Booster Shots to Maintain a ... - November 12th, 2020
- Shorter course of ADT for high-risk prostate cancer patients yields improved quality of life - November 11th, 2020
- Testosterone Litigation: What You Need To Know - MTMP - Video - November 9th, 2020
- Methadone Lowers Testosterone in Men Only - November 8th, 2020
- Should middle-aged men consider 'low T' treatment? - November 5th, 2020
- Testosterone and Crime: What Can Genes Tell Us About Behavior? - Video - October 25th, 2020
- Testosterone shown to help sexually frustrated women - October 22nd, 2020
- Testosterone levels seen prior to birth in fetus' fingers, jawline - October 20th, 2020
- Tri-Blend Testosterone. Understanding the Benefits of Testosterone Oils - October 19th, 2020
- Testosterone levels in older men - October 17th, 2020
- Tlando Testosterone Clinical Trial for Low-T and Fatty Liver Disease - October 4th, 2020
- Testosterone Focus in Diabetes Study – Video - September 30th, 2020
- Testshock Review All Natural Testosterone Enhancement – Video - September 30th, 2020
- Testosterone, Anxiety, and Depression - September 30th, 2020
- Average Testosterone Levels Decreasing Over Time Among Younger American Men - August 21st, 2020
- Testosterone Creams for Low Testosterone Treatment and Andropause - August 10th, 2020
- Testosterone Therapy and Androgen Deficiency Guide - August 6th, 2020
- Testosterone's Surprising Link to Men's 'Love Hormone' Oxytocin - August 5th, 2020
- Fortesta Brand Testosterone Therapy - August 3rd, 2020
- Andropause: Age-Associated Testosterone Decline - August 1st, 2020
- How to Build Muscle Quickly by Boosting Testosterone Levels - July 29th, 2020
- Seven Types of Drugs That Can Inhibit Sex Drive and Libido - July 22nd, 2020
- Testosterone and Geriatric Frailty - July 21st, 2020
- Testosterone and Aggression: How T-Levels Impact Human Response to External, Social Threats - July 12th, 2020
- High-Dose Testosterone Injections May Be a Viable Palliative Late-Stage Prostate Cancer Treatment - July 12th, 2020
- Could Civilization Have Been Formed as a Result of Declining Testosterone Levels in Males? - July 6th, 2020
- Testosterone Therapy Allows Man to Have the Body That He Was Meant to Have - July 5th, 2020
- Testosterone Injections for Low-T and Andropause - July 4th, 2020
- Testosterone Replacement Therapy (TRT) Reduces the Risk of Serious Adverse Health Consequences! - June 30th, 2020
- Testosterone not always to blame - Sat, 04 Aug 2012 PST - June 28th, 2020
- Five Facts About Testosterone (That Maybe You Didn't Know) - June 27th, 2020
- Manhood Washed Away: You Could Unknowingly be Annihilating Your Testosterone - June 23rd, 2020
- Testosterone: Should You Take it to Regain Your Libido and Youthful Energy? - June 22nd, 2020
- Testosterone Replacement Therapy Boosts Aerobic Capacity - June 15th, 2020
- Physiology of Testosterone - June 9th, 2020
- The Truth Behind Common Male Sex Myths - May 26th, 2020
- Dr. Andre Berger on Testosterone Deficiency in Men - Andropause Symptoms and Treatment By Doctor's Desk Series - May 21st, 2020
Word Count: 1513