Testosterone in men

Recommended by Dr. Michael White, Updated on October 20th, 2020
Reading Time: 2 minutes

The counterpart to the female menopause is called andropause (or the "male menopause"). Testosterone levels in men begin to decline with aging, beginning in the early 30s, and by age 40, levels naturally decline by one percent per year. However, the decline in male hormone production is much more gradual than the decline in female hormone production.

Testosterone performs many roles, some of which are: protecting the cardiovascular system by widening the lumen of the coronary arteries, increasing blood supply to the heart, reducing serum cholesterol and minimizing atherosclerosis, reducing high blood pressure by vasodilatation, increasing fibrinolytic activity of the blood, giving the capacity to oppose blood clot formation and dissolve blood clots. Testosterone protects against obesity and diabetes by increasing the efficacy of insulin to make glucose penetrate into the brain, the muscles, the heart and other lean tissue targets. It supports the brain and nerves by increasing blood supply and the number of connections between neurons. Bone strength and density are sustained, as well as muscle mass and strength. Testosterone improves mood and memory, reduces anxiety, and maintains sexual function.

Low levels of testosterone can result from diabetes, liver disease, hemochromatosis, obesity, smoking, chronic alcohol use, and medications such as ketoconazole, cimetidine, and glucocorticoids. Symptoms associated with low testosterone are: loss of drive and competitive edge, reduced libido, decreased level of fitness and effectiveness of workouts, joint pain and decreased muscle fitness, increased brain aging, decreased memory, and an increase in heart attack and stroke risk. Increase in fatigue, depression/mood changes and irritability. Other factors that can contribute to testosterone decline are diet and insulin resistance, stress and toxin exposure.

As men age, the balance between testosterone and estradiol might tilt in favor of estradiol production. The pituitary hormone responsible for stimulating testosterone is LH (luteinizing hormone). Too much estradiol may decrease the level of LH and, therefore, the level of testosterone.

For more than 65 years, there has been a fear that testosterone therapy will cause new prostate cancers to arise or hidden ones to grow. This long-standing fear about testosterone and prostate cancer has little scientific support, according to Abraham Morgentaler in the Canadian Journal of Urology. "Low blood levels of testosterone do not protect against prostate cancer and, indeed, may increase the risk. High blood levels of testosterone do not increase the risk of prostate cancer. Treatment with testosterone does not increase the risk of prostate cancer, even among men who are already at high risk for it."

Contraindications for testosterone therapy are: active prostatic carcinoma, breast cancer, prostate nodules or indurations, unexplained PSA elevations, erythrocytosis, unstable congestive heart failure, and severe untreated sleep apnea.

Testosterone therapy for men is based on a personal hormone test results to determine the testosterone dosage that fits the needs of the person. Bio-identical hormone replacement therapy that includes testosterone addresses the cause of the problem, not just the side effects, while offering a combination of additional long-term health benefits. Corrections to hormonal imbalances can be made via topical creams applied once or twice a day, injections or pellet insertions. We will discuss these options with you to help you decide what works for you.

For more information contact Jan Nelson at Balanced Wellness Medical Clinic, (509) 919-4575, jnelson@balancedwellnessmed.com, http://www.balancedwellnessmed.com.

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Testosterone in men

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