Video Link: https://vimeo.com/290600122
Video Download: Testosterone Replacement Therapy Boosts Aerobic Capacity
Video Stream: Testosterone Replacement Therapy Boosts Aerobic Capacity
The joint meeting of the International Society of Endocrinology and the Endocrine Society was the site of a presentation on June 22 concerning findings discovered from a clinical trial of sedentary men with low testosterone levels and mobility problems which revealed increased aerobic capacity among those treated with testosterone.
The current study evaluated data from 64 men, mean age 73, with low testosterone enrolled in the Testosterone in Older Men with Mobility Limitation Trial.
Participants in the trial were treated with 10 milligrams of testosterone in gel form or a placebo gel daily for six months.
Cycle exercise tests conducted at the beginning and end of the treatment period provided measures of aerobic function, including peak oxygen uptake and gas exchange lactate threshold.
The gas exchange lactate threshold is an excellent functional measure of the ability to do work over a prolonged period.
The rate remained steady during the 6-month study in the testosterone-treated men but declined significantly (and to a greater-than-expected extent based on average measures) in the placebo-treated controls
When the trial ended, men who received a placebo saw a drop in peak oxygen uptake, while those treated with testosterone saw an increase in their peak oxygen uptake.
Not only was the age-related decrease in peak oxygen uptake during exercise, or peak VO2 was 3.4-fold less in the testosterone-treated men than would be expected, the rate of decline in peak VO2 in placebo-treated controls was near twice the expected rate for the age-matched general population.
Researchers concluded that this accelerated decline was probably due to their limited mobility and low testosterone levels.
"We believe this is the first report of enhanced endurance performance as a result of testosterone therapy in men who have difficulty performing some physical tasks but are otherwise healthy," announced lead author Thomas W. Storer, Ph.D., who is the Director of the Exercise Physiology Laboratory at Brigham and Women's Hospital in Boston.
"At least in the short term, testosterone therapy may lessen the rate of decline of an important marker of physical fitness in older men with low testosterone...this is something we think is going to be clinically meaningful."
"These findings are potentially relevant to older men who have experienced the age-related decline in endurance capacity that may be due in part to low testosterone," he added.
"If proven safe over the long-term, restoring testosterone to normal levels may improve an important measure of physical performance and enhance their quality of life."
"We think the mechanisms involved in this benefit are many," Dr. Storer continued.
“Among them are testosterone’s demonstrated ability to increase muscle mass and thereby generate more force during exercise; increased RBC formation; stimulation of tissue capillarity to allow more blood flow to the exercising muscle; and stimulation of mitochondrial biogenesis, which increases oxygen uptake by muscle tissue.”
However, he added that although these results are quite promising, he doesn’t think this work is ready for prime time application in daily clinical practice.
He plans to further evaluate the safety of this treatment and the durability of the effects in a study with larger patient numbers and more prolonged treatment.
The study received funds from the National Institute on Aging, the Claude D. Pepper Older Americans Independence Center, and Boston University.
Dr. Storer reported having no relevant financial conflicts.
- Study Finds that Testosterone Boosts Memory for Uncontrolled Diabetics - June 24th, 2022
- Causes of Low Libido - Could It Be Low-T? - May 30th, 2022
- The Evolutionary Effects of Testosterone on Human Society - September 20th, 2021
- More Sex: A Better Way to Boost Your Testosterone Levels - September 7th, 2021
- Men Want to Know – Free Testosterone versus Total Testosterone - August 24th, 2021
- What is testosterone? - May 23rd, 2021
- Tribulus Terrestris Review Does It Raise Testosterone or ... - May 22nd, 2021
- Boosting testosterone levels (First of two parts) - May 8th, 2021
- How long does it take for Testosterone replacement treatments and therapy to work? - May 1st, 2021
- What Is Testosterone AndroGel - April 28th, 2021
- Low T - My life was falling apart because I had low testosterone - April 25th, 2021
- Deer Antler, HGH and Testosterone: Tim on Scott and BR Radio Show - Video - April 17th, 2021
- What is Testosterone? What does Testosterone do? Find on - April 14th, 2021
- How Testosterone Affects the Skin of Men - April 11th, 2021
- Testosterone, the Power Hormone - April 8th, 2021
- Testosterone Levels and Wall Street - March 27th, 2021
- Women can resist testosterone-fuelled political debate - March 12th, 2021
- BUSTED: Myths About Testosterone And Its Link To Sexual Desire In Men And Women - March 11th, 2021
- Attention Baby Boomers -- Could Testosterone be the Modern Day "Fountain of Youth?" - March 4th, 2021
- Declining Testosterone Levels in Men Not Part of Normal Aging - February 28th, 2021
- Quick Weight Loss Tips and Diet Recommendations for HRT - February 28th, 2021
- Testosterone and Alcohol: Your Health and the Holiday Season - February 27th, 2021
- Testosterone builds muscle but has risks - February 25th, 2021
- New Study Finds That Testosterone Does Not Increase Cardiovascular Risk - February 22nd, 2021
- Evidence Suggests Testosterone Plays Powerful Role in Motivating Revolutionary Change - February 15th, 2021
- The Effects of Parenthood Upon Testosterone Levels - January 9th, 2021
- Testicular Cancer Survivors are at Risk for Low Testosterone - January 6th, 2021
- Amygdala and it's Relationship to Testosterone and Fear - December 25th, 2020
- Testosterone Does Not Cause Atherosclerosis (Hardening of the Arteries) in Older Men - December 24th, 2020
- Increased Testosterone DOES NOT Cause Prostate Cancer to Spread - December 23rd, 2020
- Testosterone Cypionate and Testosterone Enanthate: The Real Facts - December 20th, 2020
- A Surprising Side Effect of Methadone Treatment: Suppressed Testosterone - December 18th, 2020
- The Testosterone Industry Globally is Booming - December 12th, 2020
- Five Benefits of Testosterone That You Need to Know - December 11th, 2020
- Testosterone Nasal Gel: A New Form of Testosterone Replacement Therapy - December 5th, 2020
- New Research Proves Testosterone Replacement Therapy is Safe for the Heart - December 3rd, 2020
- Skinny Bartender with Low Testosterone Becomes a Ripped Bodybuilder - December 3rd, 2020
- Low-T and Your Health - November 30th, 2020
- Low Testosterone Levels may Affect Man's Sex Drive and Affect his Intimate Relationships - November 19th, 2020
- Is Testosterone the New Drug of Choice on Wall Street? How Traders are Using Male Hormone Booster Shots to Maintain a ... - November 12th, 2020
- Shorter course of ADT for high-risk prostate cancer patients yields improved quality of life - November 11th, 2020
- Testosterone Litigation: What You Need To Know - MTMP - Video - November 9th, 2020
- Methadone Lowers Testosterone in Men Only - November 8th, 2020
- Intricate relationship between Oestrogen & Testosterone XXY Guys (Klinefelters' syndrome) - Video - November 7th, 2020
- Should middle-aged men consider 'low T' treatment? - November 5th, 2020
- Testosterone and Crime: What Can Genes Tell Us About Behavior? - Video - October 25th, 2020
- Testosterone shown to help sexually frustrated women - October 22nd, 2020
- Testosterone levels seen prior to birth in fetus' fingers, jawline - October 20th, 2020
- Tri-Blend Testosterone. Understanding the Benefits of Testosterone Oils - October 19th, 2020
- Testosterone levels in older men - October 17th, 2020
- Tlando Testosterone Clinical Trial for Low-T and Fatty Liver Disease - October 4th, 2020
- Testosterone Focus in Diabetes Study – Video - September 30th, 2020
- Testshock Review All Natural Testosterone Enhancement – Video - September 30th, 2020
- Testosterone, Anxiety, and Depression - September 30th, 2020
- Average Testosterone Levels Decreasing Over Time Among Younger American Men - August 21st, 2020
- Testosterone Creams for Low Testosterone Treatment and Andropause - August 10th, 2020
- Testosterone Therapy and Androgen Deficiency Guide - August 6th, 2020
- Testosterone's Surprising Link to Men's 'Love Hormone' Oxytocin - August 5th, 2020
- Fortesta Brand Testosterone Therapy - August 3rd, 2020
- Andropause: Age-Associated Testosterone Decline - August 1st, 2020
- How to Build Muscle Quickly by Boosting Testosterone Levels - July 29th, 2020
- Testosterone Deficiency Strongly Linked to Heart Attack Risk in New Study - July 26th, 2020
- Seven Types of Drugs That Can Inhibit Sex Drive and Libido - July 22nd, 2020
- Testosterone and Geriatric Frailty - July 21st, 2020
- Testosterone and Aggression: How T-Levels Impact Human Response to External, Social Threats - July 12th, 2020
- High-Dose Testosterone Injections May Be a Viable Palliative Late-Stage Prostate Cancer Treatment - July 12th, 2020
- Could Civilization Have Been Formed as a Result of Declining Testosterone Levels in Males? - July 6th, 2020
- Testosterone Therapy Allows Man to Have the Body That He Was Meant to Have - July 5th, 2020
- Testosterone Injections for Low-T and Andropause - July 4th, 2020
- Testosterone Replacement Therapy (TRT) Reduces the Risk of Serious Adverse Health Consequences! - June 30th, 2020
- Testosterone not always to blame - Sat, 04 Aug 2012 PST - June 28th, 2020
- Five Facts About Testosterone (That Maybe You Didn't Know) - June 27th, 2020
- Manhood Washed Away: You Could Unknowingly be Annihilating Your Testosterone - June 23rd, 2020
- Testosterone: Should You Take it to Regain Your Libido and Youthful Energy? - June 22nd, 2020
- Physiology of Testosterone - June 9th, 2020
- The Truth Behind Common Male Sex Myths - May 26th, 2020
- Dr. Andre Berger on Testosterone Deficiency in Men - Andropause Symptoms and Treatment By Doctor's Desk Series - May 21st, 2020
- How to Raise Testosterone Naturally. Sermorelin - Some Have Called It A The New Fountain of Youth. A Natural Cure for Anxiety and Depression. - May 9th, 2020
- Are Athletes Using Green Tea to Mask Testosterone Doping? - May 7th, 2020
- Some Animal Research Suggests that High Testosterone May Increase Prostate Cancer Risk - May 5th, 2020
Word Count: 564