Search Results for: testosterone

Reading Time: 2 minutes Public release date: 27-Mar-2012 [ | E-mail | Share ] Contact: Molly McElroy mollywmc@uw.edu 206-543-2580 University of Washington It's a rough life for the Tsimane, an isolated indigenous group in Bolivia. They make a living by hunting and foraging in forests, fishing in streams and clearing land by hand to grow crops. Their rugged lifestyle might imply that Tsimane men have elevated testosterone to maintain the physical activity required to survive each day. But new research shows that Tsimane ("chi-MAH-nay") men have a third less baseline testosterone compared with men living in the United States, where life is less physically … Read more »

Reading Time: 2 minutes Thursday, March 22, 2012 SCOTTSDALE, Ariz. Could blocking a testosterone receptor lead to a new way to treat an aggressive form of breast cancer? That's a question researchers at Mayo Clinic in Arizona and the Translational Genomics Research Institute (TGen) are exploring. Preliminary results of a Mayo Clinic TGen collaborative study shows the testosterone receptor may be a potential target to attack in treating triple negative breast cancer (TNBC). VIDEO ALERT: Click here to watch Dr. Barbara Pockaj explain the study. Lead researcher Barbara Pockaj, M.D., a surgical oncologist at Mayo Clinic in Arizona will present the results of the … Read more »

Reading Time: < 1 minute London, Mar 25 : Green tea could inadvertently help athletes who dope on testosterone as it has been found to mask the hormone's presence in urine testing. Although testosterone is naturally present in the human body, unnatural amounts of it can be spotted by detecting its unusual ratio to another hormone called epitestosterone in urine. Declan Naughton and colleagues at Kingston University London conducted lab tests and discovered that compounds called catechins - found in green and white tea but not in black - inhibit an enzyme called UGT2B17. This enzyme attaches glucuronic acid to testosterone, making it more likely … Read more »

Reading Time: 2 minutes A middle-age man goes to see his doctor, complaining of a host of vague symptoms: He's lethargic, somewhat depressed and feeling a little anxious about his manliness. Could he just need a boost of testosterone, the vital sex hormone produced by the testicles? These days, watching commercials from drug companies might lead you to believe that testosterone replacement could be just what you need, but researchers say it's unclear whether the issues associated with aging -- decreased sex drive, less energy, reduced muscle mass -- are the result of low testosterone or other factors. Often equated with youth, vigor and … Read more »

Reading Time: 2 minutes Public release date: 22-Mar-2012 [ | E-mail | Share ] Contact: Steve Yozwiak syozwiak@tgen.org 602-343-8704 The Translational Genomics Research Institute SCOTTSDALE, Ariz. -- Could blocking a testosterone receptor lead to a new way to treat an aggressive form of breast cancer? That's a question researchers at Mayo Clinic in Arizona and the Translational Genomics Research Institute (TGen) are exploring. Preliminary results of a Mayo Clinic - TGen collaborative study shows the testosterone receptor may be a potential target to attack in treating triple negative breast cancer (TNBC). Lead researcher Barbara Pockaj, M.D., a surgical oncologist at Mayo Clinic in Arizona … Read more »

Reading Time: 2 minutes The hormone makes people more egocentric and dramatically reduces cooperation between people, according to a new study of females. YuriyZhuravov/Shutterstock A study testing the effect of testosterone has found that it dramatically lowers cooperation between individuals, making people more egocentric. In this study, people performed their task more poorly under the influence of testosterone. It didn't affect their individual performance, but the lack of cooperation it caused resulted in partners making the wrong choice more frequently than they did when not under the influence of testosterone. Oh, and by the way, all the subjects were women. Self-centered, unwilling to listen, … Read more »

Reading Time: 4 minutes Testosterone therapy has been a heated issue for years among doctors and researchers, who disagree on how much it impacts heart health in men. A recent study published in the Journal of Clinical Endocrinology & Metabolism followed nearly 800 men over a ten-year period and found that those who had lower-then-average testosterone levels were 40 percent more likely to die from heart disease than those with normal levels. Similarly, a study published in the journal Diabetes Care found that men with low levels of testosterone were four times as likely to develop diabetes compared to those with optimal testosterone levels. … Read more »

Reading Time: 2 minutes Context Steroid 5-reductase inhibitors are used to treat benign prostatic hyperplasia and androgenic alopecia, but the role of 5-dihydrotestosterone (DHT) in mediating testosterone's effects on muscle, sexual function, erythropoiesis, and other androgen-dependent processes remains poorly understood. Objective To determine whether testosterone's effects on muscle mass, strength, sexual function, hematocrit level, prostate volume, sebum production, and lipid levels are attenuated when its conversion to DHT is blocked by dutasteride (an inhibitor of 5-reductase type 1 and 2). Design, Setting, and Patients The 5-Reductase Trial was a randomized controlled trial of healthy men aged 18 to 50 years comparing placebo plus testosterone … Read more »

Reading Time: < 1 minute Ugis Gruntmanis, MD Author Affiliations: Department of Medicine, Division of Endocrinology, University of Texas, Southwestern Medical Center, Dallas; and Dallas Veterans Affairs Medical Center, Dallas, Texas. Testosterone has a variety of well-known effects including bone accrual, building and maintaining muscle mass, and promoting erectile function and libido.1 Of the 5 mg of testosterone manufactured daily by the testes, about 6% to 8% is metabolized by 5-reductase to make 0.3 mg of dihydrotestosterone (DHT).2 Local conversion of testosterone to DHT by 5-reductase in the skin and prostate can create locally high concentrations of the potent androgen DHT. Dihydrotestosterone stimulates prostate growth … Read more »

Reading Time: 2 minutes Public release date: 6-Mar-2012 [ | E-mail | Share ] Contact: Gina Digravio Gina.Digravio@bmc.org 617-638-8480 JAMA and Archives Journals CHICAGO Men receiving testosterone supplementation who also received a drug (dutasteride) commonly used to treat an enlarged prostate gland and which blocks the conversion of testosterone to its potent metabolite DHT did not experience a significant difference in changes in certain outcomes such as muscle mass, muscle strength, or sexual function compared to men who did not receive dutasteride, according to a study in the March 7 issue of JAMA. Steroid 5-reductase inhibitors, which block the conversion of testosterone to DHT, … Read more »

Reading Time: 2 minutes DALLAS, March 1, 2012 /PRNewswire/ -- Low T Center opens its 8th location at 4300 133rd St, Leawood, KS 66209 on March 1st 2012. Focusing on helping revitalize men who have lowered testosterone levels, the Low T Center will be the only all-male testosterone therapy clinic in the greater Kansas City Metro Area. Currently, 13 million men in the U.S. over the age of 40 have low testosterone levels, and the center will offer solutions for these men who typically experience symptoms including fatigue, decreased energy and strength, low motivation, weight gain and even diminished sex drive. Testosterone injections do … Read more »

Reading Time: 2 minutes February 15, 2012, 5:09 PM EST By Molly Peterson (Updates with comment from analyst in fifth paragraph.) Feb. 15 (Bloomberg) -- BioSante Pharmaceuticals Inc. rose 27 percent after the testosterone replacement therapy it developed for men won U.S. regulatory approval. BioSante gained 21 cents to close at 97 cents in New York. The U.S. Food and Drug Administration announced yesterday that it approved the transdermal gel, Bio-T-Gel. The product will be marketed by Teva Pharmaceutical Industries Ltd. of Petach Tikva, Israel, for men with low testosterone levels, a condition known as hypogonadism. BioSante estimates the market for male testosterone products … Read more »

Reading Time: < 1 minute February 15, 2012, 8:39 AM EST By Molly Peterson Feb. 15 (Bloomberg) -- BioSante Pharmaceuticals Inc. surged in early trading after the testosterone replacement therapy it developed for men won U.S. regulatory approval. BioSante climbed 46 percent to $1.11 at 8:04 a.m. after the U.S. Food and Drug Administration announced the clearance yesterday. The transdermal gel, Bio-T-Gel, will be marketed by Teva Pharmaceutical Industries Ltd. of Petach Tikva, Israel, for men with low testosterone, a condition known as hypogonadism. BioSante estimates the market for male testosterone products is more than $1.2 billion in the U.S., where hypogonadism affects as many … Read more »

Reading Time: < 1 minute (Reuters) - U.S. drug regulators approved a new testosterone gel from BioSante Pharmaceutical Inc and Teva Pharmaceuticals, a Food and Drug Administration spokeswoman said. Bio-T-Gel is a topical, once-a-day gel absorbed by the skin to treat low testosterone levels in men, a condition known as hypogonadism. Shares of the specialty drugmaker BioSante spiked almost 37 percent in after-market trading on Nasdaq to $1.04. Teva shares rose 1.3 percent to $44.10. About 4 million to 5 million men in the United States suffer from low testosterone, which can cause impotence, a lack of sex drive, muscle weakness and osteoporosis, according to … Read more »

Reading Time: < 1 minute London, Feb 3 (IANS) Testosterone drives egocentricism at the cost of cooperating with others, consequently affecting group decisions, a study reveals. Collective problem solving can provide benefits over individual decisions as we are able to share our information and experiences, said a new study from Wellcome Trust's Centre for Neuroimaging at the University College London. Now researchers have shown that the testosterone has the opposite effect -- it makes people act less cooperative and more egocentric, the journal Proceedings of the Royal Society B reported. Researcher Nick Wright and colleagues at the Centre for Neuroimaging carried out a series of … Read more »

Reading Time: < 1 minute Discovered: Nuclear accidents aren't so bad; diet soda is unhealthy; why men are such jerks; a new, old crocodile; college ruins marriageability. Diet soda is unhealthy. Please, please don't take away diet soda from us, science. Last week it was caffeine and now we can't even enjoy a mid-afternoon Diet Coke break without imagining heart attacks and hospital beds. Looking at 2,564 drinkers of calorie-free soda, researchers found cola addicts were 43 percent more likely to suffer a vascular event than those who abstained. Boo. Of course calorie-free, caffeinated, fizzy deliciousness kills us. Of course. [Journal of General Internal Medicine] … Read more »

Reading Time: 2 minutes The Irish Times - Wednesday, February 1, 2012 DICK AHLSTROM, Science Editor IT CAN happen in juries and local groups, in Dáil committees and company board rooms. Too much testosterone can thwart good decision-making. People have long blamed the male hormone for damaging group dynamic and now University College London researchers have proven this to be true. Toss in some excess testosterone and co-operation tends to go out the window. Dr Nick Wright and colleagues at the Wellcome Trust Centre for Neuroimaging at UCL tested the impact of testosterone on the levels of co-operative decision-making accomplished by groups. They publish … Read more »